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PSMA1
Anti-PSMA1 Recombinant Antibody Products
- AbPlus™ Anti-PSMA1 Magnetic Beads (JB89-30) (VS-0424-XY218)
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- Target: PSMA1
- Target Species: Human, Mouse, Rat
- Application: IP, Protein Purification
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- AbPlus™ Anti-PSMA1 Magnetic Beads (VS-0724-YC1398) (VS-0724-YC1398)
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- Target: PSMA1
- Target Species: Human
- Application: IP, Protein Purification
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]
Protein class
Enzymes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Syncytiotrophoblasts)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits (PubMed:25599644, 26133119, 27342858, 27428775, 27493187, 34711951). The 20S proteasome core is a barrel-shaped complex made of 28 subunits that are arranged in four stacked rings (PubMed:25599644, 26133119, 27342858, 27428775, 27493187). The two outer rings are each formed by seven alpha subunits, and the two inner rings are formed by seven beta subunits (PubMed:25599644, 26133119, 27342858, 27428775, 27493187). The proteolytic activity is exerted by three beta-subunits PSMB5, PSMB6 and PSMB7 (PubMed:25599644, 26133119, 27342858, 27428775, 27493187). Interacts with NOTCH3 (PubMed:17292860). Interacts with ZFAND1 (PubMed:29804830).
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