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RPIA
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is an enzyme, which catalyzes the reversible conversion between ribose-5-phosphate and ribulose-5-phosphate in the pentose-phosphate pathway. This gene is highly conserved in most organisms. The enzyme plays an essential role in the carbohydrate metabolism. Mutations in this gene cause ribose 5-phosphate isomerase deficiency. A pseudogene is found on chromosome 18.
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Cytotrophoblasts, Syncytiotrophoblasts, Erythroid cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Molecular function
Isomerase
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