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SEMG1
Anti-SEMG1 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA.
Protein class
Plasma proteins
Predicted location
Secreted
Single cell type specificity
Group enriched (Basal prostatic cells, Prostatic glandular cells)
Immune cell specificity
Immune cell enriched (eosinophil)
Cell line specificity
Cell line enhanced (NTERA-2, THP-1)
Interaction
Occurs in disulfide-linked complexes which may also contain two less abundant 71- and 76-kDa semenogelin-related polypeptides. Interacts with EPPIN (via C-terminus); Cys-239 is a critical amino acid for both binding to EPPIN.
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