


SLC11A2

Anti-SLC11A2 Products
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- Species Reactivity: Human
- Application: FC, IHC-P, WB
- Anti-SLC11A2 Immunohistochemistry Kit (VS-0525-XY6622)
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- Species Reactivity: Human
- Target: SLC11A2
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Transporters
Intracellular, Membrane (different isoforms)
Cell type enhanced (Respiratory ciliated cells)
Low immune cell specificity
Low cell line specificity
Forms a complex with NDFIP1 and NEDD4L, in cortical neurons, in response to iron and colbalt exposure; this interaction leads to ubiquitination by NEDD4L and proteasome-dependent degradation. Interacts with NDFIP2. Interacts with COX2 and TOM6 at the outer mitochondrion membrane. Interacts with ARRDC1; controls the incorporation of SLC11A2 into extracellular vesicles through an ubiquitination-dependent mechanism (PubMed:27462458). Interacts with ARRDC4; controls the incorporation of SLC11A2 into extracellular vesicles through an ubiquitination-dependent mechanism (By similarity).