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TCF7L1
Loading...Anti-TCF7L1 Products
- AbPlus™ Anti-TCF7L1 Magnetic Beads (VS-0724-YC325) (VS-0724-YC325)
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- Target: TCF7L1
- Target Species: Human, Mouse
- Application: IP, Protein Purification
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- Anti-TCF7L1 Immunohistochemistry Kit (VS-0525-XY7139)
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- Species Reactivity: Human
- Target: TCF7L1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence. [provided by RefSeq, Nov 2010]
Protein class
Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Astrocytes, Leydig cells, Adipocytes)
Immune cell specificity
Immune cell enhanced (basophil)
Cell line specificity
Cell line enhanced (HBEC3-KT, NTERA-2, RH-30, T-47d)
Interaction
Binds the armadillo repeat of CTNNB1 and forms a stable complex.
Molecular function
Activator, DNA-binding, Repressor
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