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TCL1A

Anti-TCL1A Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


TCL1A is a proto - oncogene. Structurally, it encodes a small protein that lacks a classical enzymatic domain. However, it contains several phosphorylation sites that can be targeted by kinases, leading to its activation.
Protein class

Cancer-related genes, Disease related genes

Predicted location

Intracellular

Single cell type specificity

Group enriched (B-cells, dendritic cells)

Immune cell specificity

Group enriched (naive B-cell, plasmacytoid DC, memory B-cell)

Cell line specificity

Group enriched (Daudi, REH, U-698)

Interaction

Homodimer. Interacts with AKT1, AKT2 and AKT3 (via PH domain). Interacts with PNPT1; the interaction has no effect on PNPT1 exonuclease activity.

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