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USP13
Anti-USP13 Recombinant Antibody Products
- Rabbit Anti-USP13 Recombinant Antibody (clone JU72-38) (MRO-1561-CN)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, FC, IP
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- Rabbit Anti-USP13 Polyclonal Antibody (MRO-2257-CN) (MRO-2257-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, FC, IHC
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For Research Use Only. Not For Clinical Use.
Enables several functions, including BAT3 complex binding activity; chaperone binding activity; and cysteine-type peptidase activity. Involved in several processes, including maintenance of unfolded protein involved in ERAD pathway; regulation of cellular catabolic process; and regulation of transcription, DNA-templated. Acts upstream of or within protein deubiquitination and protein stabilization. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and nucleus.
Protein class
Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Cardiomyocytes, Theca cells, Inhibitory neurons)
Immune cell specificity
Immune cell enhanced (MAIT T-cell)
Cell line specificity
Cell line enhanced (HDLM-2)
Interaction
Interacts with UFD1. Interacts (via UBA domains) with SIAH2 (when ubiquitinated). Interacts with BAG6; the interaction is direct and may mediate UBL4A deubiquitination (PubMed:24424410). Interacts (via UBA 2 domain) with AMFR; the interaction is direct (PubMed:24424410). Interacts with UBL4A; may be indirect via BAG6 (PubMed:24424410).
Molecular function
Hydrolase, Protease, Thiol protease
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