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VEGFC
Anti-VEGFC Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors.
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, RAS pathway related proteins, Transporters
Predicted location
Secreted
Single cell type specificity
Cell type enhanced (Adipocytes, Microglial cells, Endothelial cells, Leydig cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced
Interaction
Homodimer; non-covalent and antiparallel (PubMed:20145116). Interacts with FLT4/VEGFR3; the interaction is required for FLT4/VEGFR3 homodimarization and activation (PubMed:23878260).
Molecular function
Developmental protein, Growth factor, Mitogen
More Types Infomation
Related Signaling Pathways
TNF Signaling Pathway