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XPOT

Anti-XPOT Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


This gene encodes a protein belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm. Translocation of tRNA to the cytoplasm occurs once exportin has bound both tRNA and GTP-bound RAN.
Protein class

Transporters

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Muller glia cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Found in a complex with XPOT, Ran and tRNA. Probably found in a complex with nucleoporins. Interacts with Ran and tRNA in a GTP-dependent manner.

Molecular function

RNA-binding, tRNA-binding

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