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YAF2
This gene encodes a zinc finger containing protein that functions in the regulation of transcription. This protein was identified as an interacting partner of transcriptional repressor protein Yy1, and also interacts with other transcriptional regulators, including Myc and Polycomb. This protein can promote proteolysis of Yy1. Multiple alternatively spliced transcript variants have been found.
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Cardiomyocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (U-937)
Interaction
Interacts with MYC, MYCN, RNF2/RING1B and YY1. Part of the E2F6. com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, L3MBTL2 and YAF2.
More Types Infomation
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IP
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For Research Use Only. Not For Clinical Use.