p97 & CD3

CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). It is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains.

p97 is a 97,000-molecular weight (MW) cell-surface glyco-protein, which is present in most human melanomas but in only trace amounts in normal tissues.