Afuco™ Anti-Human ABCB4 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-004CL)
Anti-ABCB4 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. An antibody having an antigen binding region capable of binding an epitope located in an extracellular portion of MRP3. Antibodies targeted at a MRP3 antigen present on cells expressing MRP3 and methods useful in detecting or targeting cells expression the MRP3 antigen, as well as kits, nucleic acids, polypeptides, and cells.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, plasma membrane & focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49395/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, plasma membrane & focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49395/if_selected.jpg
Figure 2 IHC staining of human liver
(Immunohistochemical staining of human liver shows strong positivity in bile canaliculi.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49395/124384_A_7_4_selected.jpg
(Immunohistochemical staining of human liver shows strong positivity in bile canaliculi.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49395/124384_A_7_4_selected.jpg
Figure 3 High expression in liver
(Hepatocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53288/166934_A_8_4.jpg
(Hepatocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53288/166934_A_8_4.jpg
Figure 4 RNA cell line category: Group enriched (SH-SY5Y, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000005471-ABCB4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000005471-ABCB4
Specifications
- Host Species
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95%, by SDS-PAGE, under reducing conditions
- Storage
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Target
- Alternative Names
- ABCB4; ATP-binding cassette, sub-family B (MDR/TAP), member 4; GBD1; ICP3; MDR2; MDR3; PGY3; ABC21; MDR2/3; PFIC-3; multidrug resistance protein 3; P-glycoprotein 3; multiple drug resistance 3; ATP-binding cassette sub-family B member 4; P glycoprotein 3/multiple drug resistance 3; P-glycoprotein-3/multiple drug resistance-3
- Gene ID
- 5244
- UniProt ID
- P21439
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0520MZ | Mouse Anti-ABCB4 Recombinant Antibody (clone Q4JJ-37) | FC, ICC, IHC-Fr, WB | Mouse IgG2b |
| VS3-QX3 | Mouse Anti-ABCB4 Recombinant Antibody (clone 1808CT346.21.23) | WB | Mouse IgG1, κ |
| VS3-FY2617 | Mouse Anti-ABCB4 Recombinant Antibody (VS3-FY2617) | WB | Mouse IgG |
| VS-0824-YJ43 | Human Anti-ABCB4 Recombinant Antibody (VS-0824-YJ43) | ELISA | Human IgG1 kappa |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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