Recombinant Anti-human BMX Intrabody [+36 GFP]
CAT#: IAB-B077(G)
Recombinant anti-BMX intrabody in fusion with +36GFP works within cells and specifically reacts with intracellur antigen BMX, expressed in 293T cells. These antibodiess bind specifically to recombinant BMX and efficiently block its kinase activity. When expressed in transformed cells, these antibodiess associated tightly with Etk, leading to significant blockade of Etk enzymatic activity and inhibition of clonogenic cell growth in soft agar.






Specifications
- Immunogen
- human BMX non-receptor tyrosine kinase
- Host Species
- human
- Type
- scFv-Tat
- Cell Penetrating Peptide
- TAT
TAT was able to deliver different proteins, such as horseradish peroxidase and RNase A across cell membrane into the cytoplasm in different cell lines in vitro. The size range of proteins with effective delivery is from 30kDa to 120-150kDa. In one study, TAT-fused proteins are rapidly internalized by lipid raft−dependent macropinocytosis using a transducible TAT−Cre recombinase reporter assay on live cells. In another study, a TAT-fused protein was delivered into mitochondria of breast cancer cells and decreased the survival of breast cancer cells, which showed capability of TAT-fusion proteins to modulate mitochondrial function and cell survival. However, very few in vivo studies have succeeded. In one study, in vivo delivery of TAT- or penetratin-crosslinked Fab fragments yielded varied organ distributions and an overall increase in organ retention, which showed tissue localization.
- Species Reactivity
- human
- Applications
- Can be useful in applications such as: Immunofluorescence; Enzyme-linked Immunosorbent Assay; Functional studies
Product Property
- Purity
- >95% (SDS-PAGE)
- Storage
- Short Term Storage: 4°C
Long Term Storage: -20°C
Target
- Alternative Names
- BMX; BMX non-receptor tyrosine kinase; ETK; PSCTK2; PSCTK3; cytoplasmic tyrosine-protein kinase BMX; NTK38 tyrosine kinase; BTK-like on X chromosome; Etk/Bmx cytosolic tyrosine kinase; epithelial and endothelial tyrosine kinase; bone marrow tyrosine kinas
- Gene ID
- 660
- UniProt ID
- P51813
Customer Review
There are currently no Customer reviews or questions for IAB-B077(G). Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "BMX"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
IAB-B077(A) | Recombinant Anti-human BMX Intrabody [(D-Arg)9] | CO-IP, FuncS | scFv-(D-Arg)9 |
IAB-B077(T) | Recombinant Anti-human BMX Intrabody [Tat] | FC, IF, FuncS | scFv-Tat |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1504MZ | Mouse Anti-BMX Recombinant Antibody (clone 2D7) | ELISA, WB | Mouse IgG1 |
ZG-0342F | Mouse Anti-Bmx Recombinant Antibody (ZG-0342F) | WB, ELISA | Mouse IgG |
VS3-QX126 | Mouse Anti-BMX Recombinant Antibody (clone 1C6) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
VS7-HM249 | Mouse Anti-BMX Recombinant Antibody (clone CBL083HM) | WB, ELISA | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0372 | Hi-Affi™ Rabbit Anti-BMX Recombinant Antibody (clone DS372AB) | WB, IP | Rabbit IgG |
Popular Products
Application: ELISA, Neut, FuncS
Application: ELISA
Application: Neut, ELISA, WB, SPR, IF, EM
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, IP, IF, FuncS, FC, Neut, ELISA
Application: ELISA, FC, IP, FuncS, IF, Neut, WB
Application: ELISA, Inhib, FC
Application: WB, ELISA, FC, IHC, IP
Application: ELISA, FC, WB, Block
Application: ELISA, FC
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: WB, ELISA, FC, IHC, IF, IP
Application: Neut, ELISA, WB, SPR, IF, EM
Application: ELISA
Application: ELISA, Neut, FuncS
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, IP, IF, FuncS, FC, Neut, ELISA
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.