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CD22
Anti-Human CD22 Recombinant Antibody (4G6)

Anti-Human CD22 Recombinant Antibody (4G6) (CAT#: TAB-1719CL)

This monoclonal antibody that specifically binds to CD22 with high affinity can be used for detecting CD22, as well as for treating various cancers and inflammatory and autoimmune disorders.

Published Data
Tested Data
Gene Expression
Datasheet
MSDS
COA

ELISA

Figure 1 is a graph shows binding of CD22 expressed on the surface of CHO cells by the anti-CD22 human antibody 4G6.

Figure 1 is a graph shows binding of CD22 expressed on the surface of CHO cells by the anti-CD22 human antibody 4G6.

Figure 1 Anti-CD22 Antibody (TAB-1719CL) in Flow Cytometry

Figure 1 Anti-CD22 Antibody (TAB-1719CL) in Flow Cytometry

Flow cytometry analysis of Daudi cells with anti-CD22 antibody (Cat#TAB-1719CL, Blue line) or isotype control antibody (Yellow line). A Goat Anti-human IgG (FITC) was used as the secondary antibody.

ELISA

Figure 2 Anti-CD22 Antibody (TAB-1719CL) in ELISA

Figure 2 Anti-CD22 Antibody (TAB-1719CL) in ELISA

ELISA analysis of TAB-1719CL was performed by coating with CD22 Protein, Human, Recombinant (His Tag).
The secondary antibody: HRP-Anti-Human IgG (H+L)

Figure 3 Anti-CD22 Antibody (TAB-1719CL) in WB

Figure 3 Anti-CD22 Antibody (TAB-1719CL) in WB

Western blot analysis of TAB-1719CL was performed with CD22 Protein, Human, Recombinant (His Tag).
TAB-1719CL incubation concentration: 2ng/μL.
The secondary antibody: HRP-Anti-Human IgG (H+L)
Lane 1: Reducing antigen (0.1μg)
Lane 2: Reducing antigen (0.3μg)
Lane 3: Reducing antigen (0.6μg)

Normal Tissue

Figure 1 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_A_7_8.jpg

Figure 2 Spleen
(Cells in red pulp
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Cells in white pulp
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_B_7_4.jpg

RNA Expression

Figure 3 RNA cell line category: Cell line enhanced (Daudi, REH, U-698, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012124-CD22

Datasheet

MSDS

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Specifications

Immunogen
The extracellular domain of human CD22 and the full-length CD22 protein expressed on CHO cells

Host Species
Human

Derivation
Human

Type
Fully human antibody

Specificity
Human

Clone
4G6

Applications
ELISA

Related Disease
Cancers and inflammatory and autoimmune disorders

Applications

Application Notes
This antibody has been reported for use in Enzyme-linked Immunosorbent Assay.

Target

Alternative Names
CD22; CD22 molecule; SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2

Gene ID
933

UniProt ID
P20273

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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CAT	Product Name	Application	Type
TAB-183-F(E)	Anti-Human CD22 Recombinant Antibody (Moxetumomab Pasudotox)	FuncS, IF, Neut, ELISA, FC, IP, ICC	Fv - disulfide stabilized
TAB-047-F(E)	Anti-Human CD22 Recombinant Antibody Fab Fragment(Bectumomab)	ELISA, FC, IP, FuncS, IF, Neut, WB	Fab' - G2a - kappa
TAB-1728CL	Anti-Human CD22 Recombinant Antibody (RFB4)	IF, FC
TAB-1714CL-S(P)	Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1714CL-S(P))	ELISA, WB	Mouse scFv
TAB-1723CL-S(P)	Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1723CL-S(P))	Inhib	Mouse scFv

CAT	Product Name	Application	Type
TAB-899	Humanized Anti-CD22 Recombinant Antibody (clone Pinatuzumab)	FC, IP, ELISA, Neut, FuncS, IF, ICC	Humanized (from mouse) IgG1, κ
TAB-1725CL-S(P)	Human Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1725CL-S(P))	Block, Cyt, ELISA, FuncS	Humanized scFv
TAB-1729CL-S(P)	Human Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1729CL-S(P))	IF, FC	Humanized scFv
TAB-002LC-S(P)	Anti-Human CD22 Recombinant Antibody scFv Fragment (VM1000)	ELISA, SPR	Humanized antibody
TAB-002LC-F(E)	Anti-Human CD22 Recombinant Antibody Fab Fragment (VM1000)	ELISA, SPR	Humanized antibody

CAT	Product Name	Application
AGTO-G077E	Anti-CD22 immunotoxin RFB4 (IgG)-PE	Cytotoxicity assay, Function study
AGTO-G077D	Anti-CD22 immunotoxin RFB4 (IgG)-DT	Cytotoxicity assay, Function study
AGTO-G077G	Anti-CD22 immunotoxin RFB4 (IgG)-Gel	Cytotoxicity assay, Function study
AGTO-G077R	Anti-CD22 immunotoxin RFB4 (IgG)-RTA	Cytotoxicity assay, Function study
AGTO-G077S	Anti-CD22 immunotoxin RFB4 (IgG)-Sap	Cytotoxicity assay, Function study

CAT	Product Name	Application	Type
TAB-0196CL	Anti-Human CD22 Recombinant Antibody (hLL2)	Inhib, Cyt, FC, WB
TAB-0197CL	Anti-Human CD22 Recombinant Antibody (hLL2-Cys)	ELISA, In vivo
TAB-0196CL-S(P)	Anti-Human CD22 Recombinant Antibody scFv Fragment (hLL2)	ELISA, In vivo
TAB-1721CL-S(P)	Anti-Human CD22 Recombinant Antibody scFv Fragment (CD22.1)	ELISA, FC, FuncS	Human antibody
TAB-1722CL-S(P)	Anti-Human CD22 Recombinant Antibody scFv Fragment (CD22.2)	ELISA, FC, FuncS	Human antibody

CAT	Product Name	Application	Type
TAB-1724CL-S(P)	Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1724CL-S(P))	Inhib	Mouse scFv
TAB-1724CL-F(E)	Human Anti-CD22 Recombinant Antibody; Fab Fragment (TAB-1724CL-F(E))	Inhib	Chimeric (mouse/human) Fab
TAB-001LC	Human Anti-CD22 Recombinant Antibody (TAB-001LC)	ELISA	Chimeric antibody (mouse/human)
TAB-001LC-S(P)	Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-001LC-S(P))	ELISA	Mouse scFv
TAB-001LC-F(E)	Human Anti-CD22 Recombinant Antibody; Fab Fragment (TAB-001LC-F(E))	ELISA	Chimeric antibody (mouse/human)

CAT	Product Name	Application	Type
Gly-001LC	Recombinant Anti-Human CD22 Antibody (Fab glycosylation)	ELISA, FC	Mouse antibody

CAT	Product Name	Application	Type
Gly-111LC	Recombinant Anti-Human CD22 Antibody (Fc glycosylation)	ELISA	Chimeric antibody (mouse/human)

CAT	Product Name	Application	Type
NEUT-315CQ	Rat Anti-CD22 Recombinant Antibody (clone 2D6)	Block	Rat IgG1, κ

CAT	Product Name	Application	Type
MOR-0545	Hi-Affi™ Rabbit Anti-CD22 Recombinant Antibody (clone DS545AB)	IP, WB	Rabbit IgG

CAT	Product Name	Application	Type
HPAB-0195-LSX	Human Anti-CD22 Recombinant Antibody (HPAB-0195-LSX)	Apop, Cyt, FC, WB, Inhib, FuncS, IF, ELISA	Human IgG
HPAB-0196-LSX	Mouse Anti-CD22 Recombinant Antibody (HPAB-0196-LSX)	ELISA, FC, IP, RIA	Mouse IgG
HPAB-0197-LSX	Human Anti-CD22 Recombinant Antibody (HPAB-0197-LSX)	ELISA, FC, FuncS	Human IgG
HPAB-0198-LSX	Mouse Anti-CD22 Recombinant Antibody (HPAB-0198-LSX)	ELISA, WB, IF, FC, SPR	Mouse IgG
HPAB-0199-LSX	Human Anti-CD22 Recombinant Antibody (HPAB-0199-LSX)	ELISA, FC	Human IgG1

CAT	Product Name	Application	Type
HPAB-0194-LSX-F(E)	Mouse Anti-CD22 Recombinant Antibody; Fab Fragment (HPAB-0194-LSX-F(E))	ELISA	Mouse Fab
HPAB-0195-LSX-F(E)	Human Anti-CD22 Recombinant Antibody; Fab Fragment (HPAB-0195-LSX-F(E))	ELISA	Human Fab
HPAB-0196-LSX-F(E)	Mouse Anti-CD22 Recombinant Antibody; Fab Fragment (HPAB-0196-LSX-F(E))	ELISA	Mouse Fab
HPAB-0197-LSX-F(E)	Human Anti-CD22 Recombinant Antibody; Fab Fragment (HPAB-0197-LSX-F(E))	ELISA	Human Fab
HPAB-0198-LSX-F(E)	Mouse Anti-CD22 Recombinant Antibody; Fab Fragment (HPAB-0198-LSX-F(E))	ELISA, FC	Mouse Fab

CAT	Product Name	Application	Type
HPAB-N0324-YC-S(P)	Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (HPAB-N0324-YC-S(P))	FuncS	Mouse scFv
HPAB-N0325-YC-S(P)	Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (HPAB-N0325-YC-S(P))	FuncS	Mouse scFv
HPAB-0709-FY-F(E)	Mouse Anti-CD22 Recombinant Antibody (clone AB008); scFv Fragment	ELISA	Mouse scFv
HPAB-0370-FY-S(P)	Human Anti-CD22 Recombinant Antibody; scFv Fragment (HPAB-0370-FY-S(P))	ELISA	Humanized scFv
HPAB-0371-FY-S(P)	Human Anti-CD22 Recombinant Antibody; scFv Fragment (HPAB-0371-FY-S(P))	Inhib	Humanized scFv

CAT	Product Name	Application	Type
AFC-TAB-176	Afuco™ Anti-CD22 ADCC Recombinant Antibody (Epratuzumab), ADCC Enhanced	IF, IP, Neut, FuncS, ELISA, FC	ADCC enhanced antibody
AFC-TAB-198	Afuco™ Anti-CD22 ADCC Recombinant Antibody (Inotuzumab), ADCC Enhanced	ELISA, FC, IP, FuncS, IF, Neut	ADCC enhanced antibody

CAT	Product Name	Application	Type
VS-0424-XY50	AbPlus Anti-CD22 Magnetic Beads (DM13)	IP, Protein Purification
VS-0724-YC918	AbPlus Anti-Cd22 Magnetic Beads (VS-0724-YC918)	IP, Protein Purification

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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