Anti-Human DDR1 Recombinant Antibody
CAT#: TAB-211CL
Recombinant Human monoclonal antibody expressed in CHO binding to Human DDR1. This is an antibody that specifically binds to the extracellular domain of human discoidin domain receptor 1 (DDR1) outside the discoidin domain, and which reduces or blocks collagen- induced autophosphorylation of DDR1 without preventing collagen binding to DDR1. Discoidin domain receptor 1 (DDR1) is a receptor tyrosine kinase that is a promising therapeutic target for a number of aggressive cancers.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & cell junctions.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/57194/if_selected.jpg
Normal Tissue
Figure 2 Lymph node
Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_A_9_8.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_B_7_5.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_A_5_6.jpg
Normal Tissue
Figure 6 Skin
Melanocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_B_7_1.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (HaCaT, HBEC3-KT, RT4, T-47d)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000204580-DDR1
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Specifications
- Host Species
- Human
- Type
- Antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95%, by SDS-PAGE with Coomassie Brilliant Blue staining
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
- Alternative Names
- DDR1; discoidin domain receptor tyrosine kinase 1; CAK; DDR; NEP; HGK2; PTK3; RTK6; TRKE; CD167; EDDR1; MCK10; NTRK4; PTK3A; epithelial discoidin domain-containing receptor 1; tyrosine kinase DDR; cell adhesion kinase; mammary carcinoma kinase 10; tyrosin
- Gene ID
- 780
- UniProt ID
- Q08345
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-176MZ | Anti-Human DDR1 Recombinant Antibody (DDR1-ab1) | FuncS | Human antibody |
| TAB-177MZ | Anti-Human DDR1 Recombinant Antibody (DDR1-ab2) | FuncS | Human antibody |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-179MZ | Anti-Human DDR1 Recombinant Antibody (AB2004) | ELISA | |
| TAB-180MZ | Anti-Human DDR1 Recombinant Antibody (AB2009) | ELISA | |
| TAB-181MZ | Anti-Human DDR1 Recombinant Antibody (AB2041) | ELISA | |
| TAB-182MZ | Mouse Anti-DDR1 Recombinant Antibody (TAB-182MZ) | FC | Mouse IgG |
| TAB-183MZ | Anti-Human DDR1 Recombinant Antibody (1F10) | WB, ELISA, FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1224CT | Recombinant Mouse anti-Human DDR1 Monoclonal antibody (3H5F23) | ELISA, IHC-P, WB | |
| VS3-WK1567 | Rabbit Anti-DDR1 Polyclonal Antibody | WB, ELISA | Rabbit IgG |
| VS4-WK140 | Human Anti-DDR1 Recombinant Antibody (clone 7F6) | ELISA | Human IgG1 |
| VS-0723-WK89 | Human Anti-DDR1 Recombinant Antibody (VS-0723-WK89) | FC | Chimeric (rabbit/human) IgG1 |
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| CAT | Product Name | Application | Type |
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| MOR-0953 | Hi-Affi™ Rabbit Anti-DDR1 Recombinant Antibody (clone DS953AB) | ELISA, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| HPAB-0061-LSX-F(E) | Mouse Anti-DDR1 Recombinant Antibody (clone AB2026); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0062-LSX-F(E) | Mouse Anti-DDR1 Recombinant Antibody (clone AB2039); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0063-LSX-F(E) | Mouse Anti-DDR1 Recombinant Antibody (clone AB2031); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0064-LSX-F(E) | Mouse Anti-DDR1 Recombinant Antibody (clone AB2074); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0125-YJ-F(E) | Human Anti-DDR1 Recombinant Antibody (clone CBD02YJ); Fab Fragment | FC, ELISA, Inhib | Human Fab |
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| VS-0724-YC1235 | AbPlus™ Anti-DDR1 Magnetic Beads (VS-0724-YC1235) | IP, Protein Purification |
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| VS-0325-XY638 | Anti-DDR1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
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