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    Recombinant Mouse anti-Human LIG3 Monoclonal antibody (2G4) (CAT#: MOB-0069CT)

    Recombinant Mouse monoclonal antibody to Human LIG3, expressed in Chinese Hamster Ovary cells(CHO).

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6723/18_F11_2_selected.jpg
    Figure 2 IHC staining of human testis
    Figure 2 IHC staining of human testis
    (Immunohistochemical staining of human testis shows strong nuclear positivity in cells in seminiferus ducts.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6723/ihc_selected.jpg
    Normal Tissue
    Figure 3 Cerebral cortex
    Figure 3 Cerebral cortex
    (Neuronal cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6723/19290_B_7_5.jpg
    Figure 4 Colon
    Figure 4 Colon
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear
    Glandular cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6723/19290_A_7_3.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Hepatocytes
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6723/19290_A_7_4.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Cells in glomeruli
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear
    Cells in tubules
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6723/19290_A_7_5.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Germinal center cells
    Staining: Low
    Intensity: Moderate
    Quantity: <25%
    Location: Nuclear
    Non-germinal center cells
    Staining: Low
    Intensity: Moderate
    Quantity: <25%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6723/19290_A_9_8.jpg
    RNA Expression
    Figure 8 RNA cell line category: Low cell line specificity
    Figure 8 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000005156-LIG3

    Specifications

    • Immunogen
    • Recombinant full length human DNA Ligase III b.
    • Host Species
    • Mouse
    • Species Reactivity
    • Human
    • Clone
    • 2G4
    • Applications
    • Used for immunoassay techniques such as: Western Blot
    • Conjugate
    • Unconjugated

    Product Property

    • Purity
    • Protein G purified
    • Format
    • Liquid
    • Concentration
    • 1.0 mg/ml
    • Buffer
    • Preservative: None Constituents: PBS, pH 7.2
    • Storage
    • Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.

    Target

    • Alternative Names
    • LIG3; ligase III, DNA, ATP-dependent; LIG2; DNA ligase 3; ligase II, DNA, ATP-dependent; polydeoxyribonucleotide synthase [ATP] 3;
    • Function
    • ATP binding; DNA binding; DNA ligase (ATP) activity; DNA ligase activity; ligase activity; metal ion binding; nucleotide binding; protein binding; zinc ion binding;

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

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    Please select product type
    Blocking Antibodies IHC Kits & Antibodies
    CAT Product Name Application Type
    NEUT-1694CQ Recombinant Mouse Anti-LIG3 Antibody (1F3) BL, ICC, IF, IP, WB IgG1

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