Human Anti-NOTCH2 Recombinant Antibody; Fab Fragment (TAB-552MZ-F(E))

Name: Human Anti-NOTCH2 Recombinant Antibody; Fab Fragment (TAB-552MZ-F(E))
SKU: TAB-552MZ-F(E)
Rating: 5 (1 reviews)

CAT#: TAB-552MZ-F(E)

This product is a recombinant human antibody Fab Fragment that recognizes NOTCH2. The antibody was purified by affinity chromatography.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line MCF7

Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & plasma membrane.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48743/714_F8_1_selected.jpg

Normal Tissue Figure 2 Cerebral cortex

Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48743/120061_B_7_5.jpg

Normal Tissue Figure 3 Colon

Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48743/120061_A_8_3.jpg

Normal Tissue Figure 4 Kidney

Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48743/120061_A_7_5.jpg

Normal Tissue Figure 5 Testis

Elongated or late spermatids Staining: Low Intensity: Moderate Quantity: <25% Sertoli cells Staining: Low Intensity: Moderate Quantity: <25%

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48743/120061_A_6_6.jpg

RNA Expression Figure 6 RNA cell line category: Low cell line specificity

Cell lines ordered by descending RNA expression order

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134250-NOTCH2

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Specifications

Host Species
Human

Type
Human Fab

Specificity
Human

Species Reactivity
Human

Applications
Enzyme-linked Immunosorbent Assay

Related Disease
Respiratory diseases such as asthma and chronic obstructive pulmonary disease

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
NOTCH2; notch 2; hN2; AGS2; HJCYS; neurogenic locus notch homolog protein 2; Notch homolog 2

Gene ID
4853

UniProt ID
Q04721

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Related Diseases

Breast Cancer

Endocrine Resistance

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-552MZ-F(E).pdf

MSDS

MSDS - TAB-552MZ-F(E).pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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See other products for "NOTCH2"

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TAB-H67	Anti-Human NOTCH2 Recombinant Antibody (TAB-H67)	FuncS, Block, ELISA	IgG2 - kappa
TAB-552MZ	Human Anti-NOTCH2 Recombinant Antibody (TAB-552MZ)	ELISA	Human IgG
TAB-552MZ-S(P)	Human Anti-NOTCH2 Recombinant Antibody; scFv Fragment (TAB-552MZ-S(P))	ELISA	Human scFv

CAT	Product Name	Application	Type
HPAB-0038-CN-S(P)	Human Anti-NOTCH2 Recombinant Antibody; scFv Fragment (HPAB-0038-CN-S(P))	FC, ELISA	Human scFv
HPAB-0039-CN-S(P)	Human Anti-NOTCH2 Recombinant Antibody; scFv Fragment (HPAB-0039-CN-S(P))	FC, ELISA	Human scFv
HPAB-0595-WJ-S(P)	Human Anti-NOTCH2 Recombinant Antibody scFv Fragment (HPAB-0595-WJ-S(P))	ELISA, WB	Human scFv
HPAB-0596-WJ-S(P)	Human Anti-NOTCH2 Recombinant Antibody scFv Fragment (HPAB-0596-WJ-S(P))	ELISA, WB	Human scFv
HPAB-0597-WJ-S(P)	Human Anti-NOTCH2 Recombinant Antibody scFv Fragment (HPAB-0597-WJ-S(P))	ELISA, WB	Human scFv

CAT	Product Name	Application	Type
HPAB-0038-CN-F(E)	Human Anti-NOTCH2 Recombinant Antibody; Fab Fragment (HPAB-0038-CN-F(E))	FC, ELISA	Human Fab
HPAB-0039-CN-F(E)	Human Anti-NOTCH2 Recombinant Antibody; Fab Fragment (HPAB-0039-CN-F(E))	FC, ELISA	Human Fab
HPAB-0595-WJ-F(E)	Human Anti-NOTCH2 Recombinant Antibody Fab Fragment (HPAB-0595-WJ-F(E))	ELISA, WB	Human Fab
HPAB-0596-WJ-F(E)	Human Anti-NOTCH2 Recombinant Antibody Fab Fragment (HPAB-0596-WJ-F(E))	ELISA, WB	Human Fab
HPAB-0597-WJ-F(E)	Human Anti-NOTCH2 Recombinant Antibody Fab Fragment (HPAB-0597-WJ-F(E))	ELISA, WB	Human Fab

CAT	Product Name	Application	Type
AFC-TAB-H67	Afuco™ Anti-NOTCH2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H67)	IF, IP, Neut, FuncS, ELISA, FC	ADCC enhanced antibody

CAT	Product Name	Application	Type
HPAB-0595-WJ	Human Anti-NOTCH2 Recombinant Antibody (HPAB-0595-WJ)	ELISA, WB	Human IgG
HPAB-0596-WJ	Human Anti-NOTCH2 Recombinant Antibody (HPAB-0596-WJ)	ELISA, WB	Human IgG
HPAB-0597-WJ	Human Anti-NOTCH2 Recombinant Antibody (HPAB-0597-WJ)	ELISA, WB	Human IgG
VS3-FY1050	Recombinant Mouse Anti-NOTCH2 Antibody (clone 2D1B2)	ELISA, IHC, ICC, FC	Mouse IgG2a
VS3-FY1051	Recombinant Mouse Anti-NOTCH2 Antibody (clone 4C5A8)	ELISA, FC	Mouse IgG1

CAT	Product Name	Application	Type
VS-0724-YC621	AbPlus™ Anti-NOTCH2 Magnetic Beads (VS-0724-YC621)	IP, Protein Purification

CAT	Product Name	Application	Type
VS-0924-YC80	Rabbit Anti-NOTCH2 Antibody (VS-0924-YC80) - Cancer Stem Cell Marker	IHC, IF	Rabbit IgG

CAT	Product Name	Application	Type
VS-0225-XY171	CytoStream™ Rat Anti-NOTCH2 Recombinant Antibody (clone 16F11)	FC	Rat IgG1, kappa

CAT	Product Name	Application	Type
VS-0425-FY160	Human Anti-NOTCH2 scFv-Fc Chimera (VS-0425-FY160)	ELISA, Block, WB	Human IgG2, scFv-Fc

CAT	Product Name	Application
VS-0325-XY1507	Anti-NOTCH2 Immunohistochemistry Kit	IHC
VS-0525-XY4909	Anti-Mouse NOTCH2 Immunohistochemistry Kit	IHC
VS-0525-XY4908	Anti-Human NOTCH2 Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0425-YC664	Recombinant Anti-NOTCH2 Vesicular Antibody, EV Displayed (VS-0425-YC664)	ELISA, FC, Cell-uptake

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