PE-A*24:02/Human GPR143 (LYSACFWWL) MHC Tetramer (CAT#: MHC-LC3295)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human GPR143 of peptide LYSACFWWL covering 126-134 and A*24:02 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Normal Tissue
RNA Expression
Figure 1 Skin 1
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3648/ihc_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3648/ihc_selected.jpg
Figure 2 Cerebral cortex
(Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3648/11323_B_7_5.jpg
(Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3648/11323_B_7_5.jpg
Figure 3 Lymph node
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3648/11323_A_8_8.jpg
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3648/11323_A_8_8.jpg
Figure 4 RNA cell line category: Cell line enriched (SK-MEL-30)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000101850-GPR143
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000101850-GPR143
Specifications
- Allele
- A*24:02
- Class
- Class I
- MHC Species
- Human
- Antigen
- GPR143
- Antigen Species
- Human
- Peptide
- LYSACFWWL
- Range
- 126-134
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y. [provided by RefSeq, Dec 2009]
- Alternative Names
- GPR143; G-protein coupled receptor 143; OA1; NYS6
- Gene ID
- 4935
- UniProt ID
- P51810
Downloads
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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