Mouse Anti-AlphaVbeta3 Recombinant Antibody (clone LM609) (CAT#: PABC-486)
This product is a recombinant Mouse antibody that can recognize alphaVbeta3. The LM609 antibody specifically recognizes αVβ3 integrin and inhibits angiogenesis, bone resorption, and viral infections in an arginine-glycine-aspartate-independent manner. LM609 binds at the interface between the β-propeller domain of the αV chain and the βI domain of the β3 chain, near the RGD-binding site, of all observed integrin conformational states.
Specific Inquiry
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human alphaVbeta3
- Species Reactivity
- Human
- Clone
- LM609
- Applications
- SPR, ELISA, FC, Inhib
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Surface Plasmon Resonance, Enzyme-linked Immunosorbent Assay, Flow Cytometry and Inhibition. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- αVβ3 integrin; alphaVbeta3
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Fab Antibody Products
ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-486 | Mouse Anti-AlphaVbeta3 Recombinant Antibody (clone LM609); Fab Fragment | ELISA, FC, Inhib | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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