Mouse Anti-CD151-integrin α6β1 complex Recombinant Antibody (clone CD1519B) (CAT#: HPAB-0258-YJ)
This product is a recombinant mouse antibody that recognizes human CD151-integrin α6β1 complex. It functions in inhibition of liver cell migration, invasion.
Specific Inquiry
Co-IP
Figure 1 Mortalin formed a complex with CD151 in .
Co-IP assay showed Mortalin formed a complex with CD151 in HCC cells.
Liu, L. X., Lu, J. C., Zeng, H. Y., Cai, J. B., Zhang, P. F., Guo, X. J., ... & Zou, H. Mortalin stabilizes CD151-depedent tetraspanin-enriched microdomains.
IF
Figure 2 Mortalin formed a complex with CD151 in .
Immunofluorescence showed colocalization of CD151 and Mortalin in HCCLM3 cells (original magnification, ×400).
Liu, L. X., Lu, J. C., Zeng, H. Y., Cai, J. B., Zhang, P. F., Guo, X. J., ... & Zou, H. Mortalin stabilizes CD151-depedent tetraspanin-enriched microdomains.
IHC
Figure 3 The expression and prognostic implication of CD151/Mortalin in HCC.
Expression of CD151 in tumor tissues was stronger than that in paratumoral tissues. Moreover, the expression of CD151 in different tumor sample had evidently variation.
Liu, L. X., Lu, J. C., Zeng, H. Y., Cai, J. B., Zhang, P. F., Guo, X. J., ... & Zou, H. Mortalin stabilizes CD151-depedent tetraspanin-enriched microdomains.
Inhib
Figure 4 Mortalin formed a complex with CD151 in .
Inhibition of Mortalin in HCC cells induced moderately decreased expression of CD151 protein, rather than CD151 mRNA. Downregulation of CD151 did not influence in the expression of Mortalin at the level of protein and mRNA.
Liu, L. X., Lu, J. C., Zeng, H. Y., Cai, J. B., Zhang, P. F., Guo, X. J., ... & Zou, H. Mortalin stabilizes CD151-depedent tetraspanin-enriched microdomains.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human CD151-integrin α6β1 complex
- Species Reactivity
- Human
- Clone
- CD1519B
- Applications
- Co-IP, IF, IHC, Inhib, WB, FuncS,
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The CD151-integrin α6β1 complex antibody has been reported in applications of Co-Immunoprecipitation, Immunofluorescence, Immunohistochemistry, Inhibition, Western Blot, Functional Assay.
Target
- Alternative Names
- CD151-integrin α6β1 complex
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0258-YJ-S(P) | Mouse Anti-CD151-integrin α6β1 complex Recombinant Antibody (clone CD1519B); scFv Fragment | WB, Inhib, FuncS | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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