Afuco™ Anti-CD22 ADCC Recombinant Antibody (Epratuzumab), ADCC Enhanced (CAT#: AFC-TAB-176)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD22. Epratuzumab is a humanized monoclonal antibody. Potential uses may be found in oncology and in treatment of inflammatory autoimmune disorders, such as lupus (SLE).
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_A_7_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_A_7_8.jpg
Figure 2 Spleen
(Cells in red pulp
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Cells in white pulp
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_B_7_4.jpg
(Cells in red pulp
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Cells in white pulp
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_B_7_4.jpg
Figure 3 RNA cell line category: Cell line enhanced (Daudi, REH, U-698, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012124-CD22
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012124-CD22
Figure 3 RNA cell line category: Cell line enhanced (Daudi, REH, U-698, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012124-CD22
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012124-CD22
Specifications
- Immunogen
- Human tonsil lymphocytes.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Clone
- Epratuzumab
- Applications
- IF, IP, Neut, FuncS, ELISA, FC
- Conjugate
- Unconjugated
- Trade name
- Lymphocide
- Generic Name
- Epratuzumab
- Related Disease
- B cell lymphoma
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Epratuzumab; LymphoCide; 205923-57-5; AMG 412; hLL2; DB04958CD22; CD22 molecule; CD22 antigen; B-cell receptor CD22; sialic acid binding Ig like lectin 2; SIGLEC 2; SIGLEC2; BL-CAM; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule;
- Gene ID
- 933
- UniProt ID
- P20273
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Epratuzumab"
Anti-Human CD22 Recombinant Antibody (Epratuzumab)Recombinant monoclonal antibody to CD22. Epratuzumab is a humanized monoclonal antibody. Potential uses may be found in oncology and in treatment of inflammatory autoimmune disorders, such as lupus (SLE).
See other products for "CD22"
Select a product category from the dropdown menu below to view related products.
Please select product type
Recombinant Antibody
Humanized Antibody
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Human Antibody
Chimeric Antibody
Mouse Antibody
Fab Glycosylation
Fc Glycosylation
Blocking Antibody
Rabbit Monoclonal Antibody
Fab Fragment Antibody
ADCC Enhanced Antibody
scFv Fragment Antibody
Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1248z | Mouse IgG1, kappa Anti-CD22 Recombinant Antibody (MOB-1248z) | IF, FC | Mouse IgG1, κ |
| HPAB-0370-FY | Human Anti-CD22 Recombinant Antibody (HPAB-0370-FY) | FC, FuncS, ELISA | Humanized IgG |
| HPAB-0371-FY | Human Anti-CD22 Recombinant Antibody (HPAB-0371-FY) | Inhib | Humanized IgG |
| MOB-260YJL | Rabbit Anti-CD22 Recombinant Antibody (clone CBR245) | WB, IP | Rabbit IgG |
| ZG-0022U | Rabbit Anti-CD22 Recombinant Antibody (clone 3D8) | ELISA, IHC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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