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    Afuco™ Anti-CD3E ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-159) (CAT#: AFC-TAB-159)

    This product is an ADCC enhanced antibody produced by our Afuco™ platform. The antibody specifically targets the CD3 epsilon chain present on T lymphocytes.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
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    Conjugation :
    Fc Engineering :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line JURKAT
    Figure 1 IF staining of human cell line JURKAT
    (Immunofluorescent staining of human cell line JURKAT shows localization to plasma membrane & endoplasmic reticulum.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40957/1970_E5_1_selected.jpg
    Normal Tissue
    Figure 2 Lymph node
    Figure 2 Lymph node
    (Non-germinal center cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72864/157655_A_9_8.jpg
    RNA Expression
    Figure 3 RNA cell line category: Group enriched (JURKAT, MOLT-4)
    Figure 3 RNA cell line category: Group enriched (JURKAT, MOLT-4)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000198851-CD3E

    Specifications

    • Immunogen
    • The details of the immunogen for this antibody are not available.
    • Host Species
    • Human
    • Derivation
    • Humanized (from mouse)
    • Type
    • ADCC enhanced antibody
    • Species Reactivity
    • Human
    • Applications
    • Neut, ELISA, IF, IP, FuncS, FC
    • Conjugate
    • Unconjugated
    • Generic Name
    • Teplizumab
    • Related Disease
    • Type 1 diabetes

    Product Property

    • Purity
    • >95% by SDS-PAGE
    • Storage
    • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Applications

    • Application Notes
    • The CD3E antibody has been reported in applications of FC, RT-PCR.

    Target

    • Alternative Names
    • T3E; TCRE; IMD18; CD3epsilon

    Related Resources

    • Biosimilar Overview
    Please refer to Teplizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Teplizumab.

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "CD3E"

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    Please select product type
    Rat Antibodies Humanized Antibodies Human Antibodies Mouse Antibodies Immunotoxins IgG Antibodies Chimeric Antibodies Rabbit Monoclonal Antibodies ScFv Antibodies Fab Antibodies ADCC Enhanced Antibodies Agonistic Antibodies Antibody Magnetic Beads NHP Antibodies FC Reagents & Kits ScFv-Fc Chimeras Extracellular Vesicle Antibodies IHC Kits & Antibodies
    CAT Product Name Application Type
    TAB-H28 Anti-Human CD3E Recombinant Antibody (Ertumaxomab) ELISA, FC, IP, FuncS, IF, Neut, ICC IgG2a / G2b

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