Mouse Anti-Histone H3K56ac Recombinant Antibody (clone 0725W24)
CAT#: VS-0725-FY184
This recombinant antibody, clone 0725W24, targets acetyl-Lys56 of human histone H3, using a peptide with this modification as its immunogen. It is validated for Chromatin Immunoprecipitation (ChIP) and Dot Blot (DB) applications. Histone H3K56ac is linked to genotoxic stress responses and cell-cycle regulation through transcription factor p53, which activates p21 Cip/WAF expression leading to cell-cycle arrest. This antibody provides a valuable tool for investigating the interplay between histone modifications and tumor suppressor pathways.
Specifications
- Immunogen
- A peptide containing acetyl-Lys56 of human histone H3.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Budding Yeast Histone H3K56ac
- Species Reactivity
- Budding Yeast, Fission Yeast, Human
- Clone
- 0725W24
- Applications
- Chromatin Immunoprecipitation, Dot Blot
- Related Disease
- Cancer, HIV latency
Product Property
- Purification
- Protein G purified
- Molecular Weight
- The molecular weight of the antigen is 17 kDa.
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol
- Preservative
- 0.035% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Chromatin Immunoprecipitation: 2-10 µg per Chromatin Immunoprecipitation
Dot Blot: 1 µg/mL
Target
- Alternative Names
- Histone H3K56ac
- Long Name
- Histone H3 Lysine 56 acetylation
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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