Human Anti-HIV-1 gp120 Recombinant Antibody (clone 23e) (CAT#: HPAB-1991-FY)
This product is a recombinant antibody that recognizes HIV-1 gp120. The monoclonal antibody 23e reacts with the epitope of HIV-1 gp120.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
IP
Figure 6 The sulfated CCR5 peptide interacts with a CD4-induced epitope of gp120 that includes tropism determinants in the V3 and C4 regions of gp120.
The gp120 glycoprotein of the R5 isolate ADA was incubated with the indicated antibodies in the presence of peptide-free buffer, the C-peptide (gray bars), or the S-peptide (black bars). The mixtures were then precipitated with the indicated antibodies, and precipitates were analyzed by SDS-PAGE. Precipitation by the 17b, A32, 48d, and 23e antibodies.
Farzan, M., Vasilieva, N., Schnitzler, C. E., Chung, S., Robinson, J., Gerard, N. P., ... & Sodroski, J. (2000). A tyrosine-sulfated peptide based on the N terminus of CCR5 interacts with a CD4-enhanced epitope of the HIV-1 gp120 envelope glycoprotein and inhibits HIV-1 entry. Journal of Biological Chemistry, 275(43), 33516-33521.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- HIV-1 gp120
- Species Reactivity
- HIV
- Clone
- 23e
- Applications
- ELISA, Inhib, RIA, Neut, IP
- Related Disease
- HIV
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 gp120 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Inhibition, Radioimmunoassay, Neutralization, Immunoprecipitation.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120; gp120; HIV envelope
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Humanized Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-135 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PGT135) | ELISA, Neut | Human IgG |
| PABL-142 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 412d) | Neut, WB, ELISA, FuncS | Human IgG |
| PABL-155 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone VRC03) | WB, ELISA, Neut, FuncS | Human IgG |
| PABL-156 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone VRC-CH31) | WB, ELISA, Neut, FuncS | Human IgG |
| PABL-160 | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone 59.1) | WB, ELISA, FuncS | Mouse IgG1, κ |
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