Human Anti-HIV-1 gp160 Recombinant Antibody (clone MO96/V3 (M096, M096/V3)) (CAT#: MRO-3791CQ)

This product is a recombinant human anti-HIV-1 monoclonal antibody. MO96/V3 (M096, M096/V3) specifically binds to gp160(309-318 + 329-338).

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Custom Production

We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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  • Published Data
  • Datasheet
  • MSDS
  • COA
Neut

Figure 1 Neutralization of infectious cell-free HIV-1 with human IgM monoclonal antibodies and controls.

Figure 1 Neutralization of infectious cell-free HIV-1 with human IgM monoclonal antibodies and controls.

The 50% inhibited HIV-1 p24 detection is indicated with the dotted line.

Devito, C., Ellegård, R., Falkeborn, T., Svensson, L., Ohlin, M., Larsson, M., ... & Hinkula, J. (2018). Human IgM monoclonal antibodies block HIV-transmission to immune cells in cervico-vaginal tissues and across polarized epithelial cells in vitro. Scientific reports, 8(1), 1-12.

Inhib

Figure 2 Inhibition of HIV-1 by human IgM monoclonal antibodies against HIV-1 envelope in human
cervical mucosa biopsies and transfer and infection of dendritic cells.

Figure 2 Inhibition of HIV-1 by human IgM monoclonal antibodies against HIV-1 envelope in human cervical mucosa biopsies and transfer and infection of dendritic cells.

The quantitative RT activity (pg/ml) in the supernatant at the end of the study period. Te bars illustrate the median and range from representative duplicate well inhibition assays.

Devito, C., Ellegård, R., Falkeborn, T., Svensson, L., Ohlin, M., Larsson, M., ... & Hinkula, J. (2018). Human IgM monoclonal antibodies block HIV-transmission to immune cells in cervico-vaginal tissues and across polarized epithelial cells in vitro. Scientific reports, 8(1), 1-12.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgM
  • Specificity
  • Recognizes HIV-1 gp160(309-318 + 329-338)
  • Species Reactivity
  • HIV-1
  • Clone
  • MO96/V3 (M096, M096/V3)
  • Applications
  • Neut, Inhib

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 gp160 antibody has been reported in applications of Neutralization, Inhibition.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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