Human Anti-HIV-1 gp160 Recombinant Antibody (clone MO97/V3) (CAT#: MRO-3792CQ)
This product is a recombinant human anti-HIV-1 monoclonal antibody. MO97/V3 specifically binds to gp160(299-308).
Specific Inquiry
Neut
Figure 1 Neutralization of infectious cell-free HIV-1 with human IgM monoclonal antibodies and controls.
The in vitro neutralizing Human anti-HIV-1 IgM MO101, MO97, and MO99, MO96 and the control nonneutralizing MO86 and MO6 with three HIV-1 isolates.
Devito, C., Ellegård, R., Falkeborn, T., Svensson, L., Ohlin, M., Larsson, M., ... & Hinkula, J. (2018). Human IgM monoclonal antibodies block HIV-transmission to immune cells in cervico-vaginal tissues and across polarized epithelial cells in vitro. Scientific reports, 8(1), 1-12.
Inhib
Figure 2 Inhibition of HIV-1 actively replicating (RT enzyme activity) from anti-HIV IgM-treated ectocervical biopsy tissue.
The quantitative RT
activity (pg/ml) in the supernatant at the end of the study period. Te bars illustrate the median and range from
representative duplicate well inhibition assays.
Devito, C., Ellegård, R., Falkeborn, T., Svensson, L., Ohlin, M., Larsson, M., ... & Hinkula, J. (2018). Human IgM monoclonal antibodies block HIV-transmission to immune cells in cervico-vaginal tissues and across polarized epithelial cells in vitro. Scientific reports, 8(1), 1-12.
Specifications
- Host Species
- Human
- Type
- Human IgM
- Specificity
- Recognizes HIV-1 gp160(299-308)
- Species Reactivity
- HIV-1
- Clone
- MO97/V3
- Applications
- Neut, Inhib
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 gp160 antibody has been reported in applications of Neutralization, Inhibition.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Fab Antibody Products
Human Antibody Products
IgG Antibody Products
ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-177 | Human Anti-HIV-1 gp160 Recombinant Antibody; Fab Fragment (PFBL-177) | WB, ELISA, Neut, FuncS | Human Fab |
| PFBL-178 | Human Anti-HIV-1 gp160 Recombinant Antibody Fab Fragment (PFBL-178) | WB, ELISA, FuncS | Human Fab |
| PFBL-179 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone PGT128); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| PFBL-180 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08C); Fab Fragment | WB, ELISA, Neut, FuncS | Human Fab |
| PFBL-181 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC13.01); Fab Fragment | FC, Neut, FuncS | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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