Human Anti-HIV-1 gp160 Recombinant Antibody (clone MO99/V3) (CAT#: MRO-3790CQ)
This product is a recombinant human anti-HIV-1 monoclonal antibody. MO99/V3 specifically binds to gp160(304-308).
Specific Inquiry
Neut
Figure 1 Neutralization of infectious cell-free HIV-1 with human IgM monoclonal antibodies and controls.
The in vitro neutralizing Human anti-HIV-1 IgM MO101, MO97, and MO99, MO96 and the control nonneutralizing MO86 and MO6 with three HIV-1 isolates.
Devito, C., Ellegård, R., Falkeborn, T., Svensson, L., Ohlin, M., Larsson, M., ... & Hinkula, J. (2018). Human IgM monoclonal antibodies block HIV-transmission to immune cells in cervico-vaginal tissues and across polarized epithelial cells in vitro. Scientific reports, 8(1), 1-12.
Inhib
Figure 2 Inhibition of transcytosis of infectious HIV-1 by human anti-HIV-1 env IgM monoclonal antibodies.
The in vitro neutralizing anti-HIV-1 IgM MO99 (p<0.01) and MO97 (p=0.05) with or without rgp160.
Devito, C., Ellegård, R., Falkeborn, T., Svensson, L., Ohlin, M., Larsson, M., ... & Hinkula, J. (2018). Human IgM monoclonal antibodies block HIV-transmission to immune cells in cervico-vaginal tissues and across polarized epithelial cells in vitro. Scientific reports, 8(1), 1-12.
Specifications
- Host Species
- Human
- Type
- Human IgM
- Specificity
- Recognizes HIV-1 gp160(304-308)
- Species Reactivity
- HIV-1
- Clone
- MO99/V3
- Applications
- Neut, Inhib
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 gp160 antibody has been reported in applications of Neutralization, Inhibition.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Human Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-554 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone C38-VRC16.01) | FC, Neut | Human IgG |
| PABL-555 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone C38-VRC18.02) | FC, Neut | Human IgG |
| PABL-556 | Human Anti-HIV-1 gp160 Recombinant Antibody (PABL-556) | Neut | Human IgG |
| PABL-557 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone Z258-VRC27.01) | FC, Neut | Human IgG |
| PABC-180 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 2558) | ELISA, Neut | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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