This product is a chimeric(chimpanzee/human) antibody that is specific for lethal factor (LF) of anthrax toxin. This antibody can be used in a variety of applications, such as ELISA, WB, Neut.
Figure 1 ELISA titration of anti-LF MAbs.
Recombinant LF was used to coat ELISA plates. Wells were then incubated with various dilutions of LF9D, LF10E, and LF11H IgGs, and the bound IgGs were detected by the addition of peroxidase-conjugated anti-human Fc antibody followed by tetramethylbenzidine substrate. OD450, optical density at 450 nm.
Chen, Z., Moayeri, M., Crown, D., Emerson, S., Gorshkova, I., Schuck, P., ... & Purcell, R. H. (2009). Novel chimpanzee/human monoclonal antibodies that neutralize anthrax lethal factor, and evidence for possible synergy with anti-protective antigen antibody. Infection and immunity, 77(9), 3902-3908.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
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CAT | Product Name | Application | Type |
---|---|---|---|
MRO-056CT-S(P) | Human Anti-LF Recombinant Antibody; scFv Fragment (MRO-056CT-S(P)) | ELISA | Human scFv |
MRO-057CT-S(P) | Anti-B. anthracis lethal factor (LF) Recombinant Antibody scFv Fragment (2LF) | ELISA, Neut | Macaque scFv |
MRO-056CT-F(E) | Human Anti-LF Recombinant Antibody; Fab Fragment (MRO-056CT-F(E)) | ELISA | Human Fab |
MRO-057CT-F(E) | Anti-B. anthracis lethal factor (LF) Recombinant Antibody Fab Fragment (2LF) | ELISA, Neut | Macaque Fab |
MRO-058CT-F(E) | Anti-B. anthracis Lethal Factor (LF) Recombinant Antibody Fab Fragment (14LF) | ELISA, Neut | Macaque Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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