Anti-S100A6 (clone W24V126) Recombinant Antibody Coupled Liposome (VS-1024-FY128) (CAT#: VS-1024-FY128)

• Potential Clinical Applications
• Glioma

• Clone
• W24V126

• Antibody Type
• IgG

• Antibody Host
• Mouse

• Antibody Reactivity
• Human

• Antibody Description
• This product is a recombinant mouse monoclonal antibody that exhibits a high degree of specificity for the human S100A6 protein. S100A6, a member of the S100 family of calcium-binding proteins, plays a crucial role in various cellular processes, including cell proliferation and differentiation. The development of this antibody provides valuable tools for research applications aiming to explore the functional significance of S100A6 in health and disease.

• Storage
• See in the COA

• Storage Shelf Time
• See in the COA

• Target
• S100A6

• Introduction
• The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.

• Alternative Names
• S100 Calcium Binding Protein A6; Prolactin Receptor-Associated Protein; Growth Factor-Inducible Protein 2A9; Calcyclin; MLN 4; CACY; PRA; S100 Calcium-Binding Protein A6 (Calcyclin)

• Full Name
• S100 Calcium Binding Protein A6

• Gene ID
• 6277

• UniProt ID
• P06703

• Sequence Similarities
• Belongs to the S-100 family.

• Cellular Localization
• Cell membrane, Cytoplasm, Membrane, Nucleus

• Post Translation Modifications
• The N-terminus is blocked.

• Protein Refseq
• NP_055439.1

• Function
• May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.

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