Human Anti-TNF Recombinant Antibody (clone F6); scFv Fragment (CAT#: HPAB-J0248-YC-S(P))
Provided is a human antibody combined with specificities of human tumor necrosis factor-Alpha (hTNF-Alpha). The antibody can neutralize the activity of hTNF-Alpha in extracorporeal tests, and can be used for detecting the hTNF-Alpha or can be applicable to treating related diseases of the hTNF-Alpha, such as rheumatoid arthritis and Crohn's disease.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Tonsil
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78469/168112_A_4_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78469/168112_A_4_8.jpg
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000232810-TNF
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000232810-TNF
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000232810-TNF
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000232810-TNF
Specifications
- Host Species
- Human
- Type
- Human scFv
- Specificity
- Human TNF
- Species Reactivity
- Human
- Clone
- F6
- Applications
- ELISA, Neut
- Related Disease
- Rheumatoid arthritis and Crohn's disease
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Tumor Necrosis Factor; Tumor Necrosis Factor Ligand Superfamily Member 2; Cachectin; TNF-Alpha; TNFSF2; TNF-A; TNFA; Tumor Necrosis Factor (TNF Superfamily, Member 2); Tumor Necrosis Factor Ligand 1F
- Gene ID
- 7124
- UniProt ID
- P01375
Related Resources
Asthma
Inflammatory Bowel Diseases
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone F6"
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Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-051 | Recombinant Anti-human TNF VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
| HPAB-AP531-YC | Camel Anti-TNF Recombinant Antibody (HPAB-AP531-YC) | ELISA | Camel VHH |
| HPAB-AP532-YC | Camel Anti-TNF Recombinant Antibody (HPAB-AP532-YC) | ELISA | Camel VHH |
| HPAB-AP533-YC | Camel Anti-TNF Recombinant Antibody (HPAB-AP533-YC) | ELISA | Camel VHH |
| HPAB-AP534-YC | Camel Anti-TNF Recombinant Antibody (HPAB-AP534-YC) | ELISA | Camel VHH |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-010 | Anti-Human TNF Recombinant Antibody (TAB-010) | WB, FC, IP, ELISA, Neut, FuncS, IF | IgG1, κ |
| TAB-111CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment (B5) | ELISA, WB | Human antibody |
| TAB-113CQ-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-113CQ-F(E)) | ELISA | Human Fab |
| TAB-135CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment (AE11-5) | ELISA, Neut | Human antibody |
| TAB-136CQ-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-136CQ-F(E)) | ELISA, Block | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-768 | Anti-TNF alpha Recombinant Antibody (Nerelimomab) | FuncS, IF, Neut, ELISA, FC, IP, ICC | IgG1 |
| TAB-311CT-S(P) | Anti-Human TNFα/RANKL Recombinant Antibody scFv Fragment (8G12) | Neut, ELISA, FC | |
| TAB-112CQ-S(P) | Anti-Human TNF Recombinant Antibody scFv Fragment (A10G10) | ELISA, WB | |
| TAB-271CQ-S(P) | Rabbit Anti-TNF Recombinant Antibody; scFv Fragment (TAB-271CQ-S(P)) | ELISA, WB | Rabbit scFv |
| TAB-271CQ-F(E) | Rabbit Anti-TNF Recombinant Antibody; Fab Fragment (TAB-271CQ-F(E)) | ELISA, WB | Rabbit Fab |
Rat Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-623CL | Bovine Anti-TNF Recombinant Antibody (TAB-623CL) | Neut | Bovine IgG |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-124CQ | Human Anti-TNF Recombinant Antibody (TAB-124CQ) | FuncS, Neut | Humanized antibody |
| TAB-125CQ | Human Anti-TNF Recombinant Antibody (TAB-125CQ) | ELISA, Neut | Humanized antibody |
| TAB-126CQ | Human Anti-TNF Recombinant Antibody (TAB-126CQ) | ELISA, Neut | Humanized antibody |
| TAB-127CQ | Human Anti-TNF Recombinant Antibody (TAB-127CQ) | ELISA, Neut | Humanized antibody |
| TAB-128CQ | Human Anti-TNF Recombinant Antibody (TAB-128CQ) | ELISA, FuncS | Humanized antibody |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-148CQ | Anti-Human TNF Recombinant Antibody | ELISA | Chimeric antibody (mouse/human) |
| TAB-148CQ-S(P) | Anti-Human TNF Recombinant Antibody scFv Fragment | ELISA | Chimeric antibody (mouse/human) |
| TAB-402CQ-S(P) | Mouse Anti-TNF Recombinant Antibody; scFv Fragment (TAB-402CQ-S(P)) | ELISA | Mouse scFv |
| TAB-148CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment | ELISA | Chimeric antibody (mouse/human) |
| TAB-402CQ-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-402CQ-F(E)) | ELISA | Chimeric (mouse/human) Fab |
Fc Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-083LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Non-hyper galactosylated) | ELISA, FC | Human antibody |
| Gly-085LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) | ELISA, FC | Human antibody |
| Gly-086LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated) | ELISA, FC | Human antibody |
| Gly-087LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated) | ELISA, FC | Human antibody |
| Gly-163LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) | ELISA | Chimeric antibody (mouse/human) |
Non-hyper Galactosylated
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-083LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Non-hyper galactosylated) | ELISA, FC | Human antibody |
Sialylated IgG Glycan
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-085LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) | ELISA, FC | Human antibody |
| Gly-163LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) | ELISA | Chimeric antibody (mouse/human) |
Hyper-galactosylated
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-086LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated) | ELISA, FC | Human antibody |
| Gly-087LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated) | ELISA, FC | Human antibody |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0609MZ | Chicken Anti-Tumor Necrosis Factor-α Polyclonal IgY | Indirect ELISA, WB | Chicken antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2051CQ | Mouse Anti-TNF Recombinant Antibody (clone CBL589) | ELISA, ICC, Neut | Mouse IgG1 |
| NEUT-2105CQ | Mouse Anti-TNF Recombinant Antibody (clone MM0N1) | Neut | Mouse IgG1 |
| NEUT-2106CQ | Mouse Anti-TNF Recombinant Antibody (clone CBL1023) | Neut | Mouse IgG1 |
| NEUT-2107CQ | Mouse Anti-TNF Recombinant Antibody (clone TNF104C) | WB, FuncS, ELISA, FC, Neut | Mouse IgG2a |
| NEUT-2108CQ | Mouse Anti-TNF Recombinant Antibody (clone mAb11) | ELISA, CyTOF, FC, ICFC, ICC, IF, IHC, Neut | Mouse IgG1, κ |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2057CQ | Rat Anti-Tnf Recombinant Antibody (clone XT3) | Block, ELISA, IHC, WB | Rat IgG1 |
| NEUT-2070CQ | Mouse Anti-TNF Recombinant Antibody (clone 4F4) | Block, ELISA, ICC, IF, IHC, WB | Mouse IgG1 |
| NEUT-2071CQ | Rabbit Anti-TNF Recombinant Antibody (clone 6E10) | Block, ELISA, IHC, WB | Rabbit IgG1 |
| NEUT-2082CQ | Mouse Anti-TNF Recombinant Antibody (clone B-C7) | Block | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4460 | Rabbit Anti-TNF Recombinant Antibody (clone SI554DS) | ELISA | Rabbit IgG |
| MOR-4461 | Rabbit Anti-TNF Recombinant Antibody (clone SI555DS) | Neut | Rabbit IgG |
| MOR-4462 | Rabbit Anti-TNF Recombinant Antibody (clone SI556DS) | FC | Rabbit IgG |
| MOR-4751 | Rabbit Anti-Tnf Recombinant Antibody (clone TH265DS) | WB | Rabbit IgG |
| MOR-4752 | Rabbit Anti-TNF Recombinant Antibody (clone TH266DS) | ELISA | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0007-YC | Human Anti-TNF Recombinant Antibody (clone cA2) | ELISA, Neut | Chimeric (mouse/human) IgG1 |
| HPAB-0046-FY | Mouse Anti-TNF Recombinant Antibody (clone 1B7) | Neut | Mouse IgG |
| HPAB-M0680-YC | Human Anti-TNF Recombinant Antibody (HPAB-M0680-YC) | ELISA, Neut, Inhib | Humanized IgG |
| HPAB-M0681-YC | Human Anti-TNF Recombinant Antibody (HPAB-M0681-YC) | ELISA, Neut, Inhib | Humanized IgG |
| HPAB-N0266-YC | Human Anti-TNF Recombinant Antibody (clone NOV005YC) | ELISA, Neut | Human IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0151-YC-S(P) | Human Anti-TNF Recombinant Antibody; scFv Fragment (HPAB-0151-YC-S(P)) | ELISA, Inhib, FuncS | Human scFv |
| HPAB-0933-FY-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-0933-FY-F(E)) | Neut, ELISA, RIA | Humanized Fab |
| HPAB-1923-FY-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-1923-FY-F(E)) | ELISA | Human Fab |
| HPAB-1924-FY-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-1924-FY-F(E)) | ELISA | Human Fab |
| HPAB-1925-FY-F(E) | Mouse Anti-TNF Recombinant Antibody (clone Mab32); scFv Fragment | ELISA | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0151-YC-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-0151-YC-F(E)) | ELISA, Inhib, FuncS | Human Fab |
| HPAB-0321CQ-F(E) | Human Anti-TNF Recombinant Antibody (clone mAb A1); Fab Fragment | ELISA, Neut | Human Fab |
| HPAB-0322CQ-F(E) | Rat Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-0322CQ-F(E)) | ELISA, FC, Inhib | Rat Fab |
| HPAB-0323CQ-F(E) | Rat Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-0323CQ-F(E)) | ELISA, FC, Inhib | Rat Fab |
| HPAB-1283LY-F(E) | Human Anti-TNF Recombinant Antibody (clone CBL026); Fab Fragment | ELISA | Human Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-768 | Afuco™ Anti-TNF ADCC Recombinant Antibody (Nerelimomab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
| AFC-TAB-006 | Afuco™ Anti-TNF ADCC Recombinant Antibody (Infliximab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-010 | Afuco™ Anti-TNF ADCC Recombinant Antibody (AFC-TAB-010), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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