Human Anti-TNF Recombinant Antibody (clone F6); Fab Fragment (CAT#: HPAB-J0248-YC-F(E))
Provided is a human antibody combined with specificities of human tumor necrosis factor-Alpha (hTNF-Alpha). The antibody can neutralize the activity of hTNF-Alpha in extracorporeal tests, and can be used for detecting the hTNF-Alpha or can be applicable to treating related diseases of the hTNF-Alpha, such as rheumatoid arthritis and Crohn's disease.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Tonsil
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78469/168112_A_4_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78469/168112_A_4_8.jpg
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000232810-TNF
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000232810-TNF
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000232810-TNF
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000232810-TNF
Specifications
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Human TNF
- Species Reactivity
- Human
- Clone
- F6
- Applications
- ELISA, Neut
- Related Disease
- Rheumatoid arthritis and Crohn's disease
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Tumor Necrosis Factor; Tumor Necrosis Factor Ligand Superfamily Member 2; Cachectin; TNF-Alpha; TNFSF2; TNF-A; TNFA; Tumor Necrosis Factor (TNF Superfamily, Member 2); Tumor Necrosis Factor Ligand 1F
- Gene ID
- 7124
- UniProt ID
- P01375
Related Resources
Asthma
Inflammatory Bowel Diseases
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Flow Cytometry (FC) related Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1076z | Mouse Anti-TNF Recombinant Antibody (clone 18C3) | ELISA, FC, FuncS | Mouse IgG1, κ |
| HPAB-0321CQ | Human Anti-TNF Recombinant Antibody (clone mAb A1) | ELISA, Neut | Human IgG |
| HPAB-0322CQ | Rat Anti-TNF Recombinant Antibody (HPAB-0322CQ) | WB, ELISA, Cyt, FuncS | Rat IgG |
| HPAB-0323CQ | Rat Anti-TNF Recombinant Antibody (HPAB-0323CQ) | ELISA, FuncS | Rat IgG |
| HPAB-0303-WJ | Human Anti-TNF Recombinant Antibody (HPAB-0303-WJ) | ELISA | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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