AbPlus™ Anti-TNFRSF10C Magnetic Beads (VS-0724-YC1229) (CAT#: VS-0724-YC1229)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-TNFRSF10C specific antibody

• Target
• TNFRSF10C

• Immunogen
• Recombinant human DcR1/TRAILR3 fragment derived from E. coli.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]

• Alternative Names
• TNF Receptor Superfamily Member 10c; Tumor Necrosis Factor Receptor Superfamily, Member 10c, Decoy Without An Intracellular Domain; TNF-Related Apoptosis-Inducing Ligand Receptor 3; Antagonist Decoy Receptor For TRAIL/Apo-2L; Decoy TRAIL Receptor Without Death Domain; Lymphocyte Inhibitor Of TRAIL; Decoy Receptor 1; TRAIL-R3; TRAILR3; DCR1;

• Gene ID
• 8794

• UniProt ID
• O14798

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