Recombinant Chimeric (Human/Mouse) Anti-VEEV Antibody (ch3B4C-4) (CAT#: FAMAB-0290YC)
A chimeric (human/mouse) monoclonal antibody (mAb) has been developed and its potential to protect from or cure a Venezuelan equine encephalomyelitis virus (VEEV) infection was evaluated. The chimeric mAb, ch3B4C-4, has virus-neutralizing capacity.
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ELISA
Figure 1 Competition ELISA with humanized HA-tagged Fab Hy4-26A (△) or murine Fab 3B4C-4 (■) on TC-83 virus.
HA-tagged Fab concentrations were held constant and were separately mixed with increasing concentrations of untagged competing 3B4C-4 Fab.
Hunt, A. R., Frederickson, S., Hinkel, C., Bowdish, K. S., & Roehrig, J. T. (2006). A humanized murine monoclonal antibody protects mice either before or after challenge with virulent Venezuelan equine encephalomyelitis virus. The Journal of general virology, 87(Pt 9), 2467–2476.
Specifications
- Host Species
- Human
- Derivation
- Chimeric (Human/Mouse)
- Type
- Chimeric (Human/Mouse) IgG1, κ
- Specificity
- VEEV
- Species Reactivity
- VEEV
- Clone
- ch3B4C-4
- Applications
- ELISA, Western Blot, Neutralization, Functional Assay
- Related Disease
- VEEV infection
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Target
- Alternative Names
- VEEV; Venezuelan equine encephalitis virus
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibodies
ScFv Antibodies
Fab Antibodies
ScFv-Fc Chimeras
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1035 | Recombinant Anti-VEEV Antibody | ELISA, WB, FC, FuncS | IgG |
| MHH-1035 | Recombinant Human Anti-VEEV Antibody | FC, WB, FuncS | IgG |
| FAMAB-0292YC | Recombinant Chimeric (Human/Mouse) Anti-VEEV Antibody (chHy4-26C) | ELISA, WB, Neut, FuncS | Chimeric (Human/Mouse) IgG1, κ |
| HPAB-0767-WJ | Recombinant Mouse Anti-VEEV Antibody (1A3B7) | WB | Mouse IgG2a |
| HPAB-0768-WJ | Recombinant Human Anti-VEEV Antibody (h1A3B7) | FC | Human IgG1 |
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