Recombinant Chimeric (Human/Mouse) Anti-VEEV Antibody (ch3B4C-4) (CAT#: FAMAB-0290YC)

A chimeric (human/mouse) monoclonal antibody (mAb) has been developed and its potential to protect from or cure a Venezuelan equine encephalomyelitis virus (VEEV) infection was evaluated. The chimeric mAb, ch3B4C-4, has virus-neutralizing capacity.


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ELISA

Figure 1 Competition ELISA with humanized HA-tagged Fab Hy4-26A (△) or murine Fab 3B4C-4 (■) on TC-83 virus.

Figure 1 Competition ELISA with humanized HA-tagged Fab Hy4-26A (△) or murine Fab 3B4C-4 (■) on TC-83 virus.

HA-tagged Fab concentrations were held constant and were separately mixed with increasing concentrations of untagged competing 3B4C-4 Fab.

Hunt, A. R., Frederickson, S., Hinkel, C., Bowdish, K. S., & Roehrig, J. T. (2006). A humanized murine monoclonal antibody protects mice either before or after challenge with virulent Venezuelan equine encephalomyelitis virus. The Journal of general virology, 87(Pt 9), 2467–2476.


Specifications

  • Host Species
  • Human
  • Derivation
  • Chimeric (Human/Mouse)
  • Type
  • Chimeric (Human/Mouse) IgG1, κ
  • Specificity
  • VEEV
  • Species Reactivity
  • VEEV
  • Clone
  • ch3B4C-4
  • Applications
  • ELISA, Western Blot, Neutralization, Functional Assay
  • Related Disease
  • VEEV infection

Product Property

  • Purity
  • >95% as determined by analysis by SDS-PAGE
  • Storage
  • Store at -20°C for long-term storage. Avoid freeze/thaw cycles.

Target

  • Alternative Names
  • VEEV; Venezuelan equine encephalitis virus

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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Recombinant Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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