Recombinant Chimeric (Human/Mouse) Anti-VEEV Antibody (chHy4-26C)
CAT#: FAMAB-0292YC
A chimeric (human/mouse) monoclonal antibody (mAb) has been developed and its potential to protect from or cure a Venezuelan equine encephalomyelitis virus (VEEV) infection was evaluated. The chimeric mAb, chHy4-26C, has virus-neutralizing capacity.
Published Data
ELISA
Figure 1 Competition ELISA with humanized HA-tagged Fab Hy4-26A (△) or murine Fab 3B4C-4 (■) on TC-83 virus.
HA-tagged Fab concentrations were held constant and were separately mixed with increasing concentrations of untagged competing 3B4C-4 Fab.
Hunt, A. R., Frederickson, S., Hinkel, C., Bowdish, K. S., & Roehrig, J. T. (2006). A humanized murine monoclonal antibody protects mice either before or after challenge with virulent Venezuelan equine encephalomyelitis virus. The Journal of general virology, 87(Pt 9), 2467–2476.
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Specifications
- Host Species
- Human
- Derivation
- Chimeric (Human/Mouse)
- Type
- Chimeric (Human/Mouse) IgG1, κ
- Specificity
- VEEV
- Species Reactivity
- VEEV
- Clone
- chHy4-26C
- Applications
- ELISA, Western Blot, Neutralization, Functional Assay
- Related Disease
- VEEV infection
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Target
- Alternative Names
- VEEV; Venezuelan equine encephalitis virus
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone chHy4-26C"
- CAT
- Product Name
See other products for "VEEV"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1035 | Recombinant Anti-VEEV Antibody | ELISA, WB, FC, FuncS | IgG |
| MHH-1035 | Recombinant Human Anti-VEEV Antibody | FC, WB, FuncS | IgG |
| FAMAB-0290YC | Recombinant Chimeric (Human/Mouse) Anti-VEEV Antibody (ch3B4C-4) | ELISA, WB, Neut, FuncS | Chimeric (Human/Mouse) IgG1, κ |
| HPAB-0767-WJ | Recombinant Mouse Anti-VEEV Antibody (1A3B7) | WB | Mouse IgG2a |
| HPAB-0768-WJ | Recombinant Human Anti-VEEV Antibody (h1A3B7) | FC | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1035-F(E) | Recombinant Anti-VEEV Antibody Fab Fragment | RIA, ELISA, FuncS | Fab |
| MHH-1035-F(E) | Recombinant Human Anti-VEEV Antibody Fab Fragment | FC, ELISA, FuncS | Fab |
| FAMAB-0290-YC-F(E) | Recombinant Human Anti-VEEV Antibody Fab Fragment (ch3B4C-4) | ELISA, WB, Neut, FuncS | Human Fab |
| HPAB-0767-WJ-F(E) | Recombinant Mouse Anti-VEEV Antibody Fab Fragment (1A3B7) | FC | Mouse Fab |
| HPAB-0768-WJ-F(E) | Recombinant Human Anti-VEEV Antibody Fab Fragment (h1A3B7) | FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-1035-S(P) | Recombinant Human Anti-VEEV Antibody scFv Fragment | ELISA, IF, FuncS | scFv |
| FAMAB-0290-YC-S(P) | Recombinant Mouse Anti-VEEV Antibody scFv Fragment (ch3B4C-4) | ELISA, WB, Neut, FuncS | Mouse scFv |
| FAMAB-0292-YC-S(P) | Recombinant Mouse Anti-VEEV Antibody scFv Fragment (chHy4-26C) | ELISA, WB, Neut, FuncS | Mouse scFv |
| HPAB-0767-WJ-S(P) | Recombinant Mouse Anti-VEEV Antibody scFv Fragment (1A3B7) | FC | Mouse scFv |
| HPAB-0768-WJ-S(P) | Recombinant Human Anti-VEEV Antibody scFv Fragment (h1A3B7) | FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY106 | Human Anti-VEEV (clone 3B4C-4) scFv-Fc Chimera | ADCC | Human IgG1, scFv-Fc |
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