Human Anti-PAG scFv-Fc Chimera (VS-0125-FY109) (CAT#: VS-0125-FY109)

• Host Species
• Human

• Type
• Human IgG1, scFv-Fc

• Species Reactivity
• Bovine

• Applications
• ELISA

• Purity
• >95% as determined by SDS-PAGE

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Buffer
• PBS

• Preservative
• No preservatives

• Stabilizer
• No Stabilizers

• Sterility
• 0.2 μM filtered

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Ice packs

• Application Notes
• The potential function of anti-scFv-Fc is to act as a capture antibody in synthetic enzyme-linked immunosorbent assays (ELISA). In this context, it could effectively bind and capture PAG, while an immune scFv could serve as a detection antibody, facilitating signal amplification and enhancing detection.

• Alternative Names
• Pregnancy-associated glycoprotein, PAG, PAG, PAPP, PAPP-A

• Function
• Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells.
  Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition.
  Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins.
  May be involved in cell adhesion signaling.

Secondary Antibody

• 2ND-029CQ
• Goat Anti-Human IgG Fc Antibody

Isotype Control

• MOB-200CQ
• Human IgG Fc Isotype Control Antibody

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