Recombinant Human Anti-CMV gB Antibody (clone TRL345-I8) (CAT#: VS-0923-XY1)

This product TRL345-I8 is a human recombinant antibody binding CMV Cytomegalovirus glycoprotein B (gB). gB is required for viral entry into host cells. The mAb targets antigenic domain 2 site 1 (AD-2S1) of gB and has high binding affinity.

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ELISA

Figure 1 ELISA testing to confirm the binding magnitude of antibody to gB AD-2S1 peptide and gB ectodomain.

Figure 1 ELISA testing to confirm the binding magnitude of antibody to gB AD-2S1 peptide and gB ectodomain.

The antibody has potent binding magnitude to gB AD-2S1 peptide and gB ectodomain.

SPR

Figure 2 SPR analysis of binding affinity of antibody for gB AD-2S1 peptide and gB ectodomain.

Figure 2 SPR analysis of binding affinity of antibody for gB AD-2S1 peptide and gB ectodomain.

The antibody has potent binding affinity against gB AD-2S1 peptide and gB ectodomain.

Neut

Figure 3 The neutralization of antibody against CMV on ARPE epithelial cells.

Figure 3 The neutralization of antibody against CMV on ARPE epithelial cells.

The antibody has potent neutralizing ability against CMV on ARPE epithelial cells.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG
  • Specificity
  • CMV gB
  • Species Reactivity
  • Cytomegalovirus (CMV)
  • Clone
  • TRL345-I8
  • Applications
  • ELISA, SPR, BLI, Neut
  • Related Disease
  • Permanent hearing loss, Cognitive impairment, Retinitis, Cerebral palsy

Product Property

  • Purification
  • Protein A affinity purified
  • Purity
  • >95%
  • Format
  • Liquid
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • ELISA: 1 μg/mL.
    Surface plasmon resonance (SPR): 10 μg/mL
    Neutralization assay: 50 μg/mL to 22.9 ng/mL

Target

  • Alternative Names
  • Cytomegalovirus glycoprotein B

Recommended Products

Recommended Dilution Buffer

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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