Recombinant Rabbit Anti-PAX6 Antibody (clone R01-1G8)
CAT#: VS3-FY1098
This product is a recombinant rabbit antibody that recognizes PAX6. This antibody has been reported for use in Western Blot. The clone R01-1G8 is specific for human PAX6. The antigen is human pax6 recombinant protein.
Gene Expression
Tested Data
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30775/1182_F2_2_red_green.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30775/371_A12_1_red_green.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30775/372_A12_1_red_green.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (AF22, AN3-CA, HEK93, HeLa, hTERT-RPE1, U-251 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000007372-PAX6
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WB
Figure 1. Recombinant Rabbit Anti-PAX6 Antibody (clone R01-1G8) in WB.
Western Blot analysis of PAX6 in K562, Hela lysates using PAX6 Antibody.
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Specifications
- Immunogen
- Human PAX6 recombinant protein.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human PAX6
- Species Reactivity
- Human
- Clone
- R01-1G8
- Applications
- Western Blot
- Conjugate
- Unconjugated
- MW
- Calculated MW: 47 kDa; Observed MW: 47 kDa
Product Property
- Purification
- Affinity Purified
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Paired Box 6; Aniridia Type II Protein; Oculorhombin; AN2; Paired Box Gene 6 (Aniridia, Keratitis); Paired Box Homeotic Gene-6; Paired Box Protein Pax-6; Aniridia, Keratitis
- Gene ID
- 5080
- UniProt ID
- P26367
- Sequence Similarities
- Belongs to the paired homeobox family.
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Ubiquitinated by TRIM11, leading to ubiquitination and proteasomal degradation.
- Protein Refseq
- NP_000271.1; NP_001121084.1; NP_001245393.1
- Function
- Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity).
Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity).
Acts as a transcriptional repressor of NFATC1-mediated gene expression (By similarity).
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "PAX6"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2602 | Hi-Affi™ Recombinant Rabbit Anti-PAX6 Monoclonal Antibody (DS2602AB) | WB, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1171-CN | Recombinant Rabbit Anti-PAX6 Monoclonal Antibody (CBACN-428) | WB, IHC, FC | Rabbit IgG |
| MRO-1172-CN | Recombinant Rabbit Anti-PAX6 Monoclonal Antibody (CBACN-429) | WB, IF, IHC | Rabbit IgG |
| VS3-CJ830 | Rabbit Anti-PAX6 Recombinant Antibody (VS3-CJ830) | WB, IHC, FC | Rabbit IgG |
| VS3-XY1214 | Mouse Anti-PAX6 Recombinant Antibody (clone 1C8) | ELISA, WB, FC | Mouse IgG1 |
| VS3-FY1815 | Rabbit Anti-PAX6 Recombinant Antibody (clone R03-8G4) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1570 | Anti-PAX6 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5207 | Anti-Mouse PAX6 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5206 | Anti-Human PAX6 Immunohistochemistry Kit | IHC |
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