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AICDA
Loading...Anti-AICDA Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, ELISA
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- Rat Anti-AICDA Recombinant Antibody (clone 0725W50) (VS-0725-FY216)
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- Species Reactivity: Human, Mouse
- Type: Rat IgG2a
- Application: ChIP, WB
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).