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ANO1
Loading...Anti-ANO1 Products
- Human Anti-ANO1 Recombinant Antibody (TAB-703CT) (TAB-703CT)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA
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- Human Anti-ANO1 Recombinant Antibody (TAB-704CT) (TAB-704CT)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA
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- Human Anti-ANO1 Recombinant Antibody; scFv Fragment (TAB-703CT-S(P)) (TAB-703CT-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: IHC, WB, ELISA
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- Human Anti-ANO1 Recombinant Antibody; scFv Fragment (TAB-704CT-S(P)) (TAB-704CT-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Human Anti-ANO1 Recombinant Antibody; Fab Fragment (TAB-703CT-F(E)) (TAB-703CT-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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- Human Anti-ANO1 Recombinant Antibody; Fab Fragment (TAB-704CT-F(E)) (TAB-704CT-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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- Mouse Anti-ANO1 Recombinant Antibody (clone EPH2.2) (MOB-2066CT)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: IHC-Fr, IHC-P
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- Human Anti-ANO1 Antibody, mRNA (TAB-041CL-mRNA)
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- Species Reactivity: Human
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- Anti-Human ANO1 Recombinant Antibody (TAB-041CL)
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- Species Reactivity: Human
- Type: Antibody
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For Research Use Only. Not For Clinical Use.
Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
Protein class
v
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Hepatocytes, Late spermatids, Breast myoepithelial cells, Early spermatids, Smooth muscle cells, Suprabasal keratinocytes, Sertoli cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (A-431, CAPAN-2, HaCaT, OE19)
Interaction
Homodimer (PubMed:21056985). Interacts with CFTR (PubMed:22178883). Interacts with TRPV4 (By similarity).
Molecular function
Chloride channel, Developmental protein, Ion channel
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