Afuco™ Anti-Human ANO1 ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-039CL
Anti-ANO1 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The TMEM16A binding molecules find uses in diagnosis and treatment of cancer, like gastrointestinal cancer, gastrointestinal stromal tumor, tumors of mesenchymal, epithelia, and all other cancers containing the 11 ql 3 amplification; as well as in diagnosis and treatment of other diseases, such as infections, inflammatory or immunological diseases.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm & plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/1715_B1_18_cr57fd049b2a359_selected.jpg
Normal Tissue
Figure 2 Seminal vesicle
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_A_7_6_val_selected.jpg
Normal Tissue
Figure 3 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Moderate Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_A_6_6.jpg
Normal Tissue
Figure 4 Salivary gland
Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_B_2_1.jpg
Normal Tissue
Figure 5 Colon
Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_A_9_3.jpg
Normal Tissue
Figure 6 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_A_7_4.jpg
RNA Expression
Figure 7 RNA cell line category: Group enriched (A-431, CAPAN-2, HaCaT, OE19)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000131620-ANO1
❮
❯
Specifications
- Host Species
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by analysis by RP-HPLC
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- ANO1; anoctamin 1, calcium activated chloride channel; DOG1; TAOS2; ORAOV2; TMEM16A; anoctamin-1; Ca2+-activated Cl- channel; oral cancer overexpressed 2; tumor-amplified and overexpressed sequence 2; discovered on gastrointestinal stromal tumors protein 1; transmembrane protein 16A (eight membrane-spanning domains)
- Gene ID
- 55107
- UniProt ID
- Q5XXA6
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for AFC-039CL. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ANO1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1781z | Mouse Anti-ANO1 Recombinant Antibody (clone 39D4) | FC, IF, IHC | Mouse IgG1, κ |
| MOB-2066CT | Mouse Anti-ANO1 Recombinant Antibody (clone EPH2.2) | IHC-Fr, IHC-P | Mouse IgG |
| VS3-XY3260 | Rabbit Anti-ANO1 Recombinant Antibody (clone R07-6V9) | IHC-P, FC | Rabbit IgG |
| VS11-QX5 | Mouse Anti-ANO1 Recombinant Antibody (clone 19F2) | IHC, WB, ELISA | Mouse IgG2b, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-703CT | Human Anti-ANO1 Recombinant Antibody (TAB-703CT) | ELISA | Human IgG1 |
| TAB-704CT | Human Anti-ANO1 Recombinant Antibody (TAB-704CT) | ELISA | Human IgG1 |
| TAB-703CT-S(P) | Human Anti-ANO1 Recombinant Antibody; scFv Fragment (TAB-703CT-S(P)) | ELISA | Human scFv |
| TAB-703CT-F(E) | Human Anti-ANO1 Recombinant Antibody; Fab Fragment (TAB-703CT-F(E)) | ELISA | Humanized Fab |
| TAB-704CT-F(E) | Human Anti-ANO1 Recombinant Antibody; Fab Fragment (TAB-704CT-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0177 | Hi-Affi™ Rabbit Anti-ANO1 Recombinant Antibody (clone DS177AB) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC339 | Recombinant Anti-ANO1 Vesicular Antibody, EV Displayed (VS-0425-YC339) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY391 | Anti-ANO1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY392 | Anti-Human ANO1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY393 | Anti-Mouse ANO1 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: WB, Neut, FuncS
-YJ-3.jpg)
Application: ELISA
Application: ELISA, WB, Neut, Funcs, IHC, Inhib
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, WB, FC, IHC, IP
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
