Mouse Anti-ANO1 Recombinant Antibody (clone 19F2)
CAT#: VS11-QX5
This product is a recombinant mouse antibody 19F2 that recognizes ANO1. This antibody can be used for the following applications: IHC, WB, ELISA.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm & plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/1715_B1_18_cr57fd049b2a359_selected.jpg
Normal Tissue
Figure 2 Seminal vesicle
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_A_7_6_val_selected.jpg
Normal Tissue
Figure 3 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Moderate Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_A_6_6.jpg
Normal Tissue
Figure 4 Salivary gland
Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_B_2_1.jpg
Normal Tissue
Figure 5 Colon
Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_A_9_3.jpg
Normal Tissue
Figure 6 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_A_7_4.jpg
RNA Expression
Figure 7 RNA cell line category: Group enriched (A-431, CAPAN-2, HaCaT, OE19)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000131620-ANO1
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Specifications
- Immunogen
- Recombinant protein DOG1
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG2b, κ
- Specificity
- Human ANO1
- Species Reactivity
- Human
- Clone
- 19F2
- Applications
- IHC, WB, ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- 1 mg/mL (Please refer to the vial label for the specific concentration.)
- Buffer
- 0.2 μm filtered solution in PBS
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipped at 4°C.
Target
- Alternative Names
- Anoctamin 1, Calcium Activated Chloride Channel; Discovered On Gastrointestinal Stromal Tumors Protein 1; Tumor-Amplified And Overexpressed Sequence 2; Oral Cancer Overexpressed 2; Transmembrane Protein 16A; TMEM16A; ORAOV2; TAOS2; DOG1; Transmembrane Protein 16A (Eight Membrane-Spanning Domains); Oral Cancer Overexpressed Protein 2; Calcium Activated Chloride Channel; Ca2+-Activated Cl- Channel
- Gene ID
- 55107
- UniProt ID
- Q5XXA6
- Long Name
- Anoctamin-1
- Sequence Similarities
- Belongs to the anoctamin family.
- Cellular Localization
- Nucleoplasm, Plasma membrane
- Function
- Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "ANO1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1781z | Mouse Anti-ANO1 Recombinant Antibody (clone 39D4) | FC, IF, IHC | Mouse IgG1, κ |
| MOB-2066CT | Mouse Anti-ANO1 Recombinant Antibody (clone EPH2.2) | IHC-Fr, IHC-P | Mouse IgG |
| VS3-XY3260 | Rabbit Anti-ANO1 Recombinant Antibody (clone R07-6V9) | IHC-P, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-703CT | Human Anti-ANO1 Recombinant Antibody (TAB-703CT) | ELISA | Human IgG1 |
| TAB-704CT | Human Anti-ANO1 Recombinant Antibody (TAB-704CT) | ELISA | Human IgG1 |
| TAB-703CT-S(P) | Human Anti-ANO1 Recombinant Antibody; scFv Fragment (TAB-703CT-S(P)) | ELISA | Human scFv |
| TAB-703CT-F(E) | Human Anti-ANO1 Recombinant Antibody; Fab Fragment (TAB-703CT-F(E)) | ELISA | Humanized Fab |
| TAB-704CT-F(E) | Human Anti-ANO1 Recombinant Antibody; Fab Fragment (TAB-704CT-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0177 | Hi-Affi™ Rabbit Anti-ANO1 Recombinant Antibody (clone DS177AB) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC339 | Recombinant Anti-ANO1 Vesicular Antibody, EV Displayed (VS-0425-YC339) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY391 | Anti-ANO1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY392 | Anti-Human ANO1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY393 | Anti-Mouse ANO1 Immunohistochemistry Kit | IHC |
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