Mouse Anti-ANO1 Recombinant Antibody (clone 19F2) (CAT#: VS11-QX5)
This product is a recombinant mouse antibody 19F2 that recognizes ANO1. This antibody can be used for the following applications: IHC, WB, ELISA.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/1715_B1_18_cr57fd049b2a359_selected.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/1715_B1_18_cr57fd049b2a359_selected.jpg
Figure 2 Seminal vesicle
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_A_7_6_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_A_7_6_val_selected.jpg
Figure 3 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Moderate Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_A_6_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Moderate Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_A_6_6.jpg
Figure 4 Salivary gland
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_B_2_1.jpg
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_B_2_1.jpg
Figure 5 Colon
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_A_9_3.jpg
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_A_9_3.jpg
Figure 6 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_A_7_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32148/77450_A_7_4.jpg
Figure 7 RNA cell line category: Group enriched (A-431, CAPAN-2, HaCaT, OE19)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000131620-ANO1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000131620-ANO1
Specifications
- Immunogen
- Recombinant protein DOG1
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG2b, κ
- Specificity
- Human ANO1
- Species Reactivity
- Human
- Clone
- 19F2
- Applications
- IHC, WB, ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- 1 mg/mL (Please refer to the vial label for the specific concentration.)
- Buffer
- 0.2 μm filtered solution in PBS
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipped at 4°C.
Target
- Alternative Names
- Anoctamin 1, Calcium Activated Chloride Channel; Discovered On Gastrointestinal Stromal Tumors Protein 1; Tumor-Amplified And Overexpressed Sequence 2; Oral Cancer Overexpressed 2; Transmembrane Protein 16A; TMEM16A; ORAOV2; TAOS2; DOG1; Transmembrane Protein 16A (Eight Membrane-Spanning Domains); Oral Cancer Overexpressed Protein 2; Calcium Activated Chloride Channel; Ca2+-Activated Cl- Channel
- Gene ID
- 55107
- UniProt ID
- Q5XXA6
- Long Name
- Anoctamin-1
- Sequence Similarities
- Belongs to the anoctamin family.
- Cellular Localization
- Nucleoplasm, Plasma membrane
- Function
- Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "ANO1"
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1781z | Mouse Anti-ANO1 Recombinant Antibody (clone 39D4) | FC, IF, IHC | Mouse IgG1, κ |
| MOB-2066CT | Mouse Anti-ANO1 Recombinant Antibody (clone EPH2.2) | IHC-Fr, IHC-P | Mouse IgG |
| VS3-XY3260 | Rabbit Anti-ANO1 Recombinant Antibody (clone R07-6V9) | IHC-P, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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