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CD2
Anti-CD2 Recombinant Antibody Products
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- Derivation: Humanized (from rat)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
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- Anti-Human CD2 Recombinant Antibody (BTI-322) (TAB-110CL)
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- Derivation: Rat
- Species Reactivity: Human
- Type: Antibody
- Application: FuncS
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- Mouse Anti-NHP CD2 Recombinant Antibody (clone RPA-2.10) (VS-1024-XY84)
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- Species Reactivity: Chimpanzee, Human, Non-human primate, Pig
- Type: Mouse IgG1, kappa
- Application: IF, FC
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For Research Use Only. Not For Clinical Use.
CD2 is a surface glycoprotein expressed on T cells, natural killer (NK) cells, and thymocytes. It functions as an adhesion molecule, interacting with ligands such as CD58 (LFA-3) on antigen-presenting cells. This interaction facilitates T cell activation and the formation of the immunological synapse. CD2 also plays a role in signal transduction, contributing to T cell proliferation and cytokine production. Its expression is essential for effective immune responses and has been studied in the context of autoimmune diseases and transplant rejection.
