CD47

Creative Biolabs is sincerely dedicated to accelerating the research and discovery process for the target CD47 by providing first-class, advanced recombinant antibodies specifically designed to target CD47. Our commitment to excellence is reflected in the meticulous development of each antibody, ensuring optimal specificity and performance for various applications. By equipping researchers with these high-quality tools, we aim to facilitate significant advancements in understanding CD47's role in immunology and cancer research, ultimately supporting groundbreaking discoveries that can lead to innovative therapeutic strategies.

CD47: A Significant Surface Protein in Cancer

CD47 is a cell surface protein that plays a crucial role in regulating immune responses. It is often referred to as a "don't eat me" signal, as it inhibits phagocytosis by macrophages. Research on CD47 is of significant importance as it holds potential in the treatment of various diseases, especially cancers. By targeting CD47, it is possible to enhance the immune system's ability to recognize and eliminate cancer cells. This could lead to the development of novel and more effective cancer therapeutics. Additionally, understanding the function of CD47 in immune regulation may provide insights into treating other immune-related disorders.

Alternative Names

CD47 molecule; IAP; OA3; MER6

Background

CD47 (CD47 Molecule) is a Protein Coding gene. Diseases associated with CD47 include Hereditary Spherocytosis and Neonatal Meningitis. Among its related pathways is the response to elevated platelet cytosolic Ca2+ and the Innate Immune System. Gene Ontology (GO) annotations related to this gene include thrombospondin receptor activity.

Anti-CD47 rAb Products

Our company is determined to hasten research and discovery by offering high-quality anti-CD47 recombinant antibody products at an extraordinary value together with superior technical support.

Creative Quality Control

Creative Biolabs has set up a rigorous quality management system to ensure the quality of our antibody products. Simultaneously, it helps our clients save time during the drug development process and fulfills their research and development requirements.

Customer Reviews

Excellent

C**re
Human Anti-CD47 Recombinant Antibody (Cat#: TAB-303LC)

In my study related to immune disorders, I made use of the Human Anti-CD47 Recombinant Antibody. When using ELISA for assessment, the outcome was highly encouraging. The antibody effectively identified CD47, offering clear and consistent results. It proved to be an invaluable tool, facilitating my research and providing crucial insights into the mechanisms underlying immune dysregulation involving CD47.

25/Aug/2022

Excellent

H**in
Human Anti-CD47 Recombinant Antibody (Cat#: HPAB-0096-CN)

I used the human anti-CD47 recombinant antibody in my study on cancer immunotherapy. I employed flow cytometry and neutralization assays for evaluation. The results were quite remarkable. With FC, it precisely identified the binding of the antibody to CD47 on tumor cells. The neutralization assays demonstrated its effective blocking of the CD47 signaling pathway, suggesting potential therapeutic efficacy.

17/Feb/2023

Excellent

W**er
Mouse Anti-CD47 Recombinant Antibody (clone MABL-1) (Cat#: HPAB-1278WJ)

I employed the mouse anti-CD47 recombinant antibody in my study on tumor microenvironment. I conducted detection through ELISA and Inhibition assays. ELISA offered clear measurements of CD47 expression, while the Inhibition assays showcased its potential in modulating related pathways. The antibody was essential for my study, enabling me to make significant progress and obtain conclusive results.

8/Apr/2023

Anti-CD47 rAb Production

Our company's platform has many years of experience in aspects such as vector construction and antibody production. Therefore, we have the ability to provide high-quality antibody production services for research professionals.

Featured Anti-CD47 Recombinant Antibody Production Platforms
Fig.6 Milligram-scale recombinant antibody production.

Fig.7 Gram-scale recombinant antibody production

rAb Modalities

After years of exploration, Creative Biolabs can provide researchers with the most comprehensive and advanced high-quality recombinant antibodies of various types to meet the diverse research and development needs of customers.

Fig.8 Full Length Anti-CD47 Recombinant Antibody Production and Modalities

Drug Information Targeting CD47

Table 1. Therapeutic approaches targeting CD47 in clinical development.

For additional information on our anti-CD47 recombinant antibody products, please do not hesitate to reach out to us. Our team is eager to provide assistance and answer any questions you may have. We look forward to fostering a friendly and productive collaboration that supports your research endeavors.