CD59 & CD38

CD59 encodes a glycoprotein that inhibits complement-mediated cell lysis. It prevents the formation of the membrane attack complex (MAC) by binding to the C8 and C9 components of the complement system. CD59 plays an important role in protecting host cells from complement-mediated damage and is involved in maintaining immune homeostasis. Mutations in CD59 can lead to increased susceptibility to infections and hemolysis.

CD38 (CD38 Molecule) is a Protein Coding gene. Diseases associated with CD38 include Richter's Syndrome and Leukemia, Chronic Lymphocytic. Among its related pathways are Cell-type Dependent Selectivity of CCK2R Signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include transferase activity and hydrolase activity, acting on glycosyl bonds. An important paralog of this gene is BST1.