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CD59 & CD38
Engineered Antibody Products
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AbPlus
Recombinant Antibody Products
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Anti-CD59 & CD38 Recombinant Antibody Products
- Rat Anti-CD38 Recombinant Antibody (clone NIMR-5) (NEUT-349CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG2a, κ
- Application: Neut, FC, IHC-Fr, IP, BA
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- Mouse Anti-CD59 Recombinant Antibody (clone MEM-43) (NEUT-397CQ)
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: Neut, FC, IHC, IHC-P, IP, CyTOF®
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- Rat Anti-CD59 Recombinant Antibody (clone YTH53.1) (NEUT-398CQ)
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- Species Reactivity: Human
- Type: Rat IgG2b
- Application: Block, FC, ICC, IF, IHC-Fr, IHC-P, WB, FuncS
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For Research Use Only. Not For Clinical Use.
CD59 encodes a glycoprotein that inhibits complement-mediated cell lysis. It prevents the formation of the membrane attack complex (MAC) by binding to the C8 and C9 components of the complement system. CD59 plays an important role in protecting host cells from complement-mediated damage and is involved in maintaining immune homeostasis. Mutations in CD59 can lead to increased susceptibility to infections and hemolysis.
CD38 (CD38 Molecule) is a Protein Coding gene. Diseases associated with CD38 include Richter's Syndrome and Leukemia, Chronic Lymphocytic. Among its related pathways are Cell-type Dependent Selectivity of CCK2R Signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include transferase activity and hydrolase activity, acting on glycosyl bonds. An important paralog of this gene is BST1.
