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CD72
Anti-CD72 Recombinant Antibody Products
- Anti-CD72 (clone 10D6.8.1)-SPP-DM1 ADC (ADC-177LZY)
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- Target: CD72
- Linker: SPP (N-succinimidyl-4-(2-pyridyldithio)pentanoate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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- Anti-CD72 (clone 10D6.8.1)-MCC-DM1 ADC (ADC-178LZY)
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- Target: CD72
- Linker: MCC (Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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- Anti-CD72 (clone 10D6.8.1)-mc-vc-PABC-MMAE ADC (ADC-179LZY)
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- Target: CD72
- Linker: mc-VC-PABC (maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAE (monomethyl auristatin E)
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- Anti-CD72 (clone 10D6.8.1)-mc-MMAF ADC (ADC-180LZY)
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- Target: CD72
- Linker: mc (maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
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For Research Use Only. Not For Clinical Use.
Plays a role in B-cell proliferation and differentiation
Protein class
CD markers
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (B-cells, Kupffer cells, Macrophages, NK-cells, Hofbauer cells, dendritic cells)
Immune cell specificity
Group enriched (naive B-cell, memory B-cell)
Cell line specificity
Cell line enhanced (Daudi, Karpas-707, REH, U-698)
Interaction
Homodimer; disulfide-linked. Associates with CD5. Interacts (tyrosine phosphorylated) with PTPN6/SHP-1 (By similarity).
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