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For Research Use Only. Not For Clinical Use.
Creative Biolabs is fully committed to advancing the research and discovery of the target DLK1. By offering exceptional, state-of-the-art recombinant antibodies tailored specifically for DLK1, we aim to make a significant impact on scientific progress. Our innovative products utilize the latest technology to guarantee high specificity and reliability, empowering researchers to achieve groundbreaking results in their studies. With a strong emphasis on quality and performance, we are dedicated to supporting your research efforts and enhancing our understanding of the crucial roles DLK1 plays in various biological processes.
The target DLK1, a transmembrane protein expressed in multiple tissues and cell types, is involved in various biological processes including cell differentiation, proliferation, apoptosis, and tissue regeneration. Research on DLK1 is significant as it can offer insights into embryonic development and tissue homeostasis. Additionally, it has been implicated in several diseases such as cancer, neurodegenerative disorders, and metabolic disorders. Thus, understanding its role in these diseases may lead to the development of new diagnostic and therapeutic strategies. Moreover, DLK1 may serve as a potential target for drug development. Targeting it with specific inhibitors or antibodies could have therapeutic benefits in diseases where it is overexpressed or dysregulated. In conclusion, DLK1 is an important research target with significant implications for human health.
Delta like non-canonical Notch ligand 1; DLK; DLK-1; Delta1; FA1; PREF1; Pref-1; ZOG; pG2
This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that function as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing uniparental disomy and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal.
Intracellular, Membrane (different isoforms)
Cell type enhanced (Skeletal myocytes, Leydig cells, Fibroblasts, Exocrine glandular cells)
Not detected in immune cells
Group enriched (AF22, Hep G2, SH-SY5Y)
Monomer. Interacts with SH3RF2 (By similarity).
We are dedicated to offering high-quality and superior antibody products. These are intended to satisfy the research requirements of a broad spectrum of researchers when it comes to the target DLK1 and its functions. Our goal is to assist their scientific investigations and promote progress in this area.
Cat. No. | Product Name | Target Species | Host Species | Applications |
TAB-206MZ | Anti-Human DLK1 Recombinant Antibody (B09) | Human | Human | ELISA; WB; IP |
TAB-207MZ | Anti-Human DLK1 Recombinant Antibody (A04) | Human | Human | ELISA; WB; IP |
HPAB-0789-CN | Mouse Anti-DLK1 Recombinant Antibody | Human | Mouse | ELISA; FC; IHC |
TAB-203MZ | Mouse Anti-DLK1 Recombinant Antibody | Human | Mouse | FC; FuncS |
TAB-204MZ | Mouse Anti-DLK1 Recombinant Antibody | Human | Mouse | FC; FuncS |
To fulfill the needs of our customers, we have implemented a series of rigorous quality management systems throughout the production process of antibody products to guarantee their superior quality.
Fig.1 ELISA analysis of anti-DLK1 antibody (Cat# TAB-206MZ, Creative Biolabs).
We provide comprehensive one-stop services that cover an extensive range from gene synthesis to the production of high-quality recombinant antibodies. Our team of experts is committed to ensuring every step is carried out with excellence. Thanks to this extensive service offering, we are entirely capable of providing customers with superior antibody production services that meet their diverse needs.
Featured Anti-DLK1 Recombinant Antibody Production Platforms
Fig.2 Milligram-scale recombinant antibody production.
Fig.3 Gram-scale recombinant antibody production.
Creative Biolabs is firmly committed to providing researchers with the most comprehensive and cutting-edge high-quality recombinant antibodies in diverse formats. We strive to meet the diverse needs of scientific research by offering a wide range of antibody options to facilitate advanced research endeavors.
Fig.4 Full Length Anti-DLK1 Recombinant Antibody Production and Modalities.
Table 1. Therapeutic approaches targeting DLK1 in clinical development.
Research phase | Company | Classification | Indications | Details |
Phase I | TORL Biotherapeutics | Antibody-Drug Conjugates (ADCs) | Cancer | It is an antibody-drug conjugate targeting delta like non-canonical notch ligand 1 (DLK1) in early clinical development at TORL Biotherapeutics for the treatment of advanced solid tumors. |
Phase I | ADC Therapeutics | Antibody-Drug Conjugates (ADCs) | Cancer | This is an antibody-drug conjugate developed by ADC Therapeutics in early clinical development for the intravenous treatment of neuroendocrine tumors and carcinomas. |
Phase I | ADC Therapeutics | Humanized Monoclonal Antibodies | Cancer | It is an afucosylated humanized antibody targeting cell surface antigen DLK-1, in early clinical development at Chiome Bioscience for the treatment of solid tumors. |
If you are seeking more information about our anti-DLK1 recombinant antibody products, please don't hesitate to contact us. Our team is ready to provide you with all the details you need to make informed decisions. We are eager to establish a mutually beneficial partnership that enhances your research initiatives and contributes to the advancement of your scientific endeavors.