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GCC2
Anti-GCC2 Recombinant Antibody Products
- Recombinant Anti-Human GCC2 Antibody (MOB-3017z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, IF, FuncS
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- Rabbit Anti-GCC2 Polyclonal Antibody (CBPAB-055LC)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IF, IHC
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- Recombinant Anti-Human GCC2 Antibody Fab Fragment (MOB-3017z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IP, FuncS
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- Recombinant Anti-Human GCC2 Antibody scFv Fragment (MOB-3017z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: FC, WB, FuncS
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a peripheral membrane protein localized to the trans-Golgi network. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. Alternative splicing results in multiple transcript variants.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homodimer. Interacts (via GRIP domain) with RAB6A (preferentially in its GTP-bound form). May interact (RAB6A-dependent) with ARL1; according to PubMed:19703403, RAB6A and ARL1 are not involved in GCC2 Golgi localization as proposed by PubMed:18243103. Interacts (probably via GRIP domain) with RAB9A (preferentially in its GTP-bound form). Interacts with CLASP1 and CLASP2; recruits both proteins to membranes of the TGN. Interacts with STX16.
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