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HER3 & EGFR
Loading...Anti-HER3 & EGFR Products
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
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- Target: EGFR
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Mouse
- Cytokine 1 Species: Human
- Molecule Class: IL2-IgG2a
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- Derivation: Humanized (from rat)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: Neut, ELISA, IF, IP, FuncS, FC, WB
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG2 - kappa
- Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, IP, FC, FuncS, Neut, IF, IHC
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: FC, IP, ELISA, Neut, FuncS, IF, WB
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- Derivation: Chimeric
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, WB
- Anti-Human EGFR Recombinant Antibody (ABT-806) (TAB-228CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Antibody
- Application: WB, IHC
- Mouse Anti-EGFR Recombinant Antibody (TAB-271MZ) (TAB-271MZ)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: FuncS
- Human Anti-EGFR Recombinant Antibody (TAB-272MZ) (TAB-272MZ)
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- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: FuncS
- Human Anti-EGFR Recombinant Antibody (TAB-0225CL) (TAB-0225CL)
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- Derivation: Chimeric (Mouse/Human)
- Species Reactivity: Human
- Type: Chimeric (Mouse/Human) IgG1
- Application: Block, Inhib, FuncS, Apop, In vivo
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC
- Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-270MZ-F(E)) (TAB-270MZ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-EGFR Recombinant Antibody (TAB-270MZ) (TAB-270MZ)
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: FuncS
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- Species Reactivity: Human
- Type: Human IgG
- Application: Block
- Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-272MZ-F(E)) (TAB-272MZ-F(E))
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- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: FuncS
- Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-308MZ-F(E)) (TAB-308MZ-F(E))
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- Species Reactivity: Human
- Type: Chimeric antibody (mouse/human)
- Application: ELISA, FC
- Human Anti-EGFR Recombinant Antibody (TAB-278MZ) (TAB-278MZ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: Cyt, ELISA, Inhib
- Human Anti-EGFR Recombinant Antibody (TAB-274MZ) (TAB-274MZ)
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- Species Reactivity: Human
- Type: Humanized IgG
- Application: FC
- Anti-Human EGFR Recombinant Antibody Fab Fragment (L4-H3) (TAB-309MZ-F(E))
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- Type: Humanized antibody
- Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-274MZ-F(E)) (TAB-274MZ-F(E))
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- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Chimeric (Human/Mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: Neut, ELISA, IF, IP, FuncS, FC, WB
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- Derivation: Chimeric (human/mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IF, WB, Inhib
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- Species Reactivity: Human
- Type: Human IgG
- Application: FC
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB
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- Derivation: Humanized
- Species Reactivity: Human
- Type: ADCC enhanced antibody
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB, FuncS
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, WB, FuncS
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, ELISA, FC, IF, IHC, FuncS
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- Derivation: Humanized
- Species Reactivity: Human
- Type: IgG1
- Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
- Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-278MZ-F(E)) (TAB-278MZ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB
- Anti-Human EGFR Recombinant Antibody Fab Fragment (EG-26-11) (TAB-314MZ-F(E))
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- Derivation: Library
- Type: Human antibody
- Application: ELISA, FC
- Anti-Human EGFR Recombinant Antibody Fab Fragment (528) (TAB-315MZ-F(E))
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- Type: Human antibody
- Application: WB, FC
- Human Anti-EGFR Recombinant Antibody (TAB-283MZ) (TAB-283MZ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: Cyt, FuncS, Inhib
- Rabbit Anti-Human EGFR (phospho Y1068) Antibody (MOB-0243MC)
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- Species Reactivity: Human, Mouse, Rat
- Application: IHC, WB
- Human Anti-EGFR Recombinant Antibody (TAB-279MZ) (TAB-279MZ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: Cyt, ELISA, Inhib
- Anti-Human EGFR Recombinant Antibody Fab Fragment (EG-19-11) (TAB-313MZ-F(E))
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- Derivation: Library
- Type: Human antibody
- Application: ELISA, FC
- Human Anti-EGFR Recombinant Antibody (TAB-282MZ) (TAB-282MZ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: Cyt, FuncS, Inhib
- Rabbit Anti-Human EGFR (phospho Y1092) Antibody (MOB-0242MC)
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- Species Reactivity: Rat, Human
- Application: IHC, WB
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- Target: EGFR
- Species Reactivity: Human
- Cytokine 1: TNFα
- Host: Mouse
- Cytokine 1 Species: Human
- Molecule Class: TNF-IgG2a
- Anti-Human EGFR Recombinant Antibody Fab Fragment (LA22) (TAB-277MZ-F(E))
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- Application: MTT assay
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: Block
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- Target: EGFR
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Chimeric (Mouse-Human)
- Cytokine 1 Species: Human
- Molecule Class: IgG-IL2
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB, FuncS
- Anti-Human EGFR Recombinant Antibody Fab Fragment (07D06) (TAB-316MZ-F(E))
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- Application: WB, MTT assay
- Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-0564CL-S(P)) (TAB-0564CL-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-0564CL-F(E)) (TAB-0564CL-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: Mouse
- Type: Llama VHH
- Application: ELISA, IHC, FC, FuncS
- Anti-Human EGFR Recombinant Antibody Fab Fragment (LA1) (TAB-276MZ-F(E))
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- Application: MTT assay
- Mouse Anti-EGFR Recombinant Antibody (TAB-0564CL) (TAB-0564CL)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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- Derivation: Llama
- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, ELISA
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- Derivation: Llama
- Species Reactivity: Human
- Type: Llama VHH
- Application: FuncS, ELISA, IF
- 10-FnIII scaffold protein anti-Human EGFR (SFN-L003)
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- Scaffold Name: 10-FnIII
- Target: EGFR
- Species Reactivity: Human
- Derivation: Phage display
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- Derivation: Llama
- Species Reactivity: Human
- Type: Llama VHH
- Application: FuncS, SPR
- Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-310MZ-F(E)) (TAB-310MZ-F(E))
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- Species Reactivity: Human, Monkey
- Type: Mouse Fab
- Application: ELISA
- Anti-Human EGFR Recombinant Antibody (LA22) (TAB-277MZ)
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- Application: Cyt, FuncS
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- Species Reactivity: Human
- Type: Human Fab
- Application: Block
- Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-275MZ-F(E)) (TAB-275MZ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC
- Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-311MZ-F(E)) (TAB-311MZ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Anti-Human EGFR Recombinant Antibody (LA1) (TAB-276MZ)
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- Application: Cyt, FuncS
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: FuncS
- Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-306MZ-F(E)) (TAB-306MZ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-307MZ-F(E)) (TAB-307MZ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC
- Anti-EGFR Antibody-Cytokine Fusion Protein, IgG-IL2 (ACFP-SH155)
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- Target: EGFR
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Humanized from Mouse
- Cytokine 1 Species: Human
- Molecule Class: IgG1-IL2
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC
- Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-312MZ-F(E)) (TAB-312MZ-F(E))
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- Species Reactivity: Human, Monkey
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Human scFv
- Application: Block
- Mouse Anti-EGFR Recombinant Antibody (TAB-281MZ) (TAB-281MZ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IF, IHC
- Mouse Anti-EGFR Recombinant Antibody (TAB-275MZ) (TAB-275MZ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: Cyt, FuncS, Inhib
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC
- Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-273MZ-F(E)) (TAB-273MZ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC
- Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-271MZ-F(E)) (TAB-271MZ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FuncS
- Mouse Anti-EGFR Recombinant Antibody (TAB-273MZ) (TAB-273MZ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, FuncS, IHC, IP, Inhib
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB, FuncS
- Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-0565CL-F(E)) (TAB-0565CL-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Anti-EGFR-mc-MMAF ADC (ADC-039CL)
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- Target: EGFR
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-EGFR (J2898A)-SMCC-DM1 ADC (IMGN289) (ADC-L016)
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- Target: EGFR
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto- 1-oxopropyl)maytansine)
- Anti-EGFR-MC-VC-PABA-MMAE ADC (ADC-038CL)
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- Target: EGFR
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Cetuximab (Gly-015CL)
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- CAS number: 205923-56-4
- Anti-EGFR-EDC/NHS-methotrexate ADC (ADC-060LZY)
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- Target: EGFR
- Linker: EDC/NHS
- Drug: MTX
- Anti-EGFR (ABT-806)-Mc-MMAE ADC (ABT-414) (ADC-L001)
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- Target: EGFR
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-EGFR-vc-Duostatin-3 ADC (ADC-088LZY)
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- Target: EGFR
- Linker: VC (valine-citrulline)
- Drug: Duostatin-3
- Anti-EGFR-doxorubicin ADC (ADC-168LZY)
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- Target: EGFR
- Linker: polyethylene glycol linker
- Drug: doxorubicin
- Anti-EGFR (clone Antibody 1)-MC-MMAF ADC (ADC-059CL)
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- Target: EGFR
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
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- Targets: HER3 & EGFR
- Type: Tandem Diabody
- Application: FuncS, Promising therapeutic agent
- Anti-EGFRvIII-SMCC-DM1 ADC (ADC-048LZY)
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- Target: EGFRvIII
- Linker: SMCC (N-succinimidyl-4-(N-maleimidomethyl)-cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-EGFR (clone J2898A)-SMCC-DM1 ADC (ADC-047LZY)
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- Target: EGFR
- Linker: SMCC (N-succinimidyl-4-(N-maleimidomethyl)-cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-EGFR (clone Bat0206)-S-3AA-MDC ADC (ADC-157CL)
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- Target: EGFR
- Linker: S-3AA
- Drug: MDC (maytansinol)
- Anti-EGFR (clone Bat0206)-SMCC-MDC ADC (ADC-158CL)
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- Target: EGFR
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: MDC (maytansinol)
- Anti-EGFR-MCC-Dox ADC (ADC-057LZY)
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- Target: EGFR
- Linker: MCC (4-(N-maleimidomethyl)cyclohexane-1-carboxylate)
- Drug: doxorubicin
- Anti-EGFR-vc-PAB-MODO ADC (ADC-263CL)
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- Target: epidermal growth factor receptor (EGFR)
- Linker: VC-PAB (valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MODO (monomethyldolastatin)
- Anti-EGFR-SMCC-methotrexate ADC (ADC-059LZY)
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- Target: EGFR
- Linker: SMCC (N-succinimidyl-4-(N-maleimidomethyl)-cyclohexane-1-carboxylate)
- Drug: MTX
- Anti-EGFR-MC-VC-PABA-MMAE ADC (ADC-037CL)
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- Target: EGFR
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-EGFR-EDC/NHS-Dox ADC (ADC-058LZY)
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- Target: EGFR
- Linker: EDC/NHS(1-ethyl-3-(3-diaminopropyl)carbodiimide/N-hydroxysuccinimide)
- Drug: doxorubicin
- Anti-EGFR (clone ABT-806)-mc-MMAF ADC (ADC-071LZY)
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- Target: EGFR
- Linker: mc (maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
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For Research Use Only. Not For Clinical Use.
Background
Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin. Isoform 2 may act as an antagonist of EGF action.


Bladder Cancer
Non-small Cell Lung Cancer
Pancreatic Cancer
Hepatocellular Carcinoma
Cushing Syndrome
JAK-STAT Signaling Pathway
