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    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

    Anti-Human EGFR Recombinant Antibody (ABT-806) (CAT#: TAB-228CL)

    Recombinant Chimeric (human/mouse) monoclonal antibody expressed in CHO binding to Human EGFR. This is a novel EGFR antibody that selectively targets a tumor-selective epitope suggesting that a mAb 806-based therapeutic would retain antitumor activity without the on-target toxicities associated with EGFR inhibition.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line A-431
    Figure 1 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cell junctions.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/144_E9_2_selected.jpg
    Figure 2 IF staining of human cell line U-251 MG
    Figure 2 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/143_E9_1_blue_red_green.jpg
    Normal Tissue
    Figure 3 Colon
    Figure 3 Colon
    (Glandular cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_9_3.jpg
    Figure 4 Liver
    Figure 4 Liver
    (Cholangiocytes
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_7_4.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Bowman's capsule
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Collecting ducts
    Staining:Medium
    Intensity: Strong
    Quantity: <25%
    Distal tubules
    Staining:Medium
    Intensity: Strong
    Quantity: <25%
    Proximal tubules (cell body)
    Staining:Medium
    Intensity: Strong
    Quantity: <25%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_9_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Leydig cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Pachytene spermatocytes
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Round or early spermatids
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_6_6.jpg
    Figure 7 Placenta
    Figure 7 Placenta
    (Cytotrophoblasts
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Decidual cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Hofbauer cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Syncytiotrophoblasts - cell body
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Syncytiotrophoblasts - microvilli
    Staining:High
    Intensity: Strong)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_1_7.jpg
    Figure 8 Lymph node
    Figure 8 Lymph node
    (Non-germinal center cells
    Staining:Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_7_8.jpg
    RNA Expression
    Figure 9 RNA cell line category: Cell line enriched (A-431)
    Figure 9 RNA cell line category: Cell line enriched (A-431)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000146648-EGFR

    Specifications

    • Host Species
    • Human
    • Derivation
    • Humanized
    • Type
    • Antibody
    • Species Reactivity
    • Human
    • Applications
    • WB, IHC
    • Related Disease
    • Cancer

    Product Property

    • Purity
    • >95%, by SDS-PAGE, under reducing conditions
    • Storage
    • 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.

    Applications

    • Application Notes
    • This antibody has been reported for use in Western Blot and Immunohistochemistry.

    Target

    • Alternative Names
    • EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1;

    Related Resources

    • Related Diseases
    • Related Signaling Pathways

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "EGFR"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    Chimeric Antibody Products ScFv Antibody Products IgG Antibody Products Mouse Antibody Products Human Antibody Products Humanized Antibody Products Fc Glycosylation Antibody Products High-mannose Glycoform Antibody Products Deglycosylated Antibody Products Chicken IgY Antibody Products MHC Tetramer Products for Cancer Neutralizing Antibody Products Rabbit Monoclonal Antibody Products Fab Antibody Products ADCC Enhanced Antibody Products Single Domain Antibody Products Antibody Magnetic Beads Cancer Stem Cell Biomarker Specific Antibody Products Non-Human Primate (NHP) Antibody Products ScFv-Fc Chimera Products Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    TAB-750 Anti-EGFR/HER1 Recombinant Antibody (TAB-750) Neut, ELISA, IF, IP, FuncS, FC, WB IgG1 - kappa
    TAB-0225CL Human Anti-EGFR Recombinant Antibody (TAB-0225CL) Block, Inhib, FuncS, Apop, In vivo Chimeric (Mouse/Human) IgG1
    TAB-0225CL-S(P) Human Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-0225CL-S(P)) Block, Inhib, FuncS, Apop, In vivo Human scFv
    TAB-308MZ-S(P) Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-308MZ-S(P)) ELISA, FC Mouse scFv
    PABX-051-F (E) Recombinant Mouse Anti-EGFR Antibody Fab Fragment (Matuzumab) WB, Neut, FuncS Fab

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    Cite This Product

    To accurately reference this product in your publication, please use the following citation information:

    (Creative Biolabs Cat# TAB-228CL, RRID: AB_3111887)

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